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ChemicalBook >  Product Catalog >  Analytical Chemistry >  Standard >  Pharmaceutical Impurity Reference Standards >  (S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine hydrochloride

(S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine hydrochloride

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(S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine hydrochloride Basic information

Product Name:
(S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine hydrochloride
Synonyms:
  • (S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine hydrochloride
  • Duloxetine impurity F
  • (S)-(+)-N-methyl-3-(1-naphthalenyloxy)-3-(3-thienyl)propanamine
  • Duloxetine EP Impurity F HCl
  • Duloxetine-7
  • 3-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyloxy)-, (γS)
  • (3S)-N-Methyl-γ-(1-naphthalenyloxy)-3-thiophenepropanamine
  • Duloxetine EP Impurity FQ: What is Duloxetine EP Impurity F Q: What is the CAS Number of Duloxetine EP Impurity F Q: What is the storage condition of Duloxetine EP Impurity F Q: What are the applications of Duloxetine EP Impurity F
CAS:
959392-22-4
MF:
C18H19NOS
MW:
297.41
Mol File:
959392-22-4.mol
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(S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine hydrochloride Chemical Properties

Boiling point:
466.2±40.0 °C(Predicted)
Density 
1.158±0.06 g/cm3(Predicted)
pka
10.12±0.10(Predicted)
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(S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine hydrochloride Usage And Synthesis

Uses

(γS)-N-Methyl-γ-(1-naphthalenyloxy)-3-thiophenepropanamine (Duloxetine EP Impurity F) is an impurity of Duloxetine (D721000), an antidepressant and a dual serotonin and norepinephrine reuptake inhibitor (SNRI) (1,2). Exhibits linear pharmacokinetics in mice and is not associated in any drastic changes of blood pressure or heart rate (3).

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