Dibucaine hydrochloride
Dibucaine hydrochloride Basic information
- Product Name:
- Dibucaine hydrochloride
- Synonyms:
-
- 2-butoxy-n-(2-(diethylamino)ethyl)-4-quinolinecarboxamidmonohydrochlorid
- Dibucaine (Cinchocaine) HCl
- 2-butoxy-n-(2-(diethylamino)ethyl)-cinchoninamidmonohydrochloride
- 2-butoxy-n-(2-diethylaminoethyl)cinchoninicacidamidehydrochloride
- 2-n-butoxy-n-(2-diethylaminoethyl)cinchoninamidehydrochloride
- 4-Quinolinecarboxamide,2-butoxy-N-[2-(diethylamino)ethyl]-,monohydrochloride
- benzolin(localanesthetic)
- butoxycinchoninicaciddiethylethylenediamidehydrochloride
- CAS:
- 61-12-1
- MF:
- C20H30ClN3O2
- MW:
- 379.92
- EINECS:
- 200-498-1
- Product Categories:
-
- API
- NUPERCAINAL
- Amines
- Heterocycles
- Intermediates & Fine Chemicals
- Other APIs
- Pharmaceuticals
- API
- Mol File:
- 61-12-1.mol
Dibucaine hydrochloride Chemical Properties
- Melting point:
- 99-101 °C(lit.)
- Density
- 1.1338 (rough estimate)
- refractive index
- 1.5400 (estimate)
- storage temp.
- Refrigerator
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- color
- Hygroscopic crystals
- PH
- pH(20g/l,25℃) : 5.0～6.0
- Water Solubility
- Freely soluble in water, alcohol, acetone, or chloroform
- Merck
- 13,3057
- Stability:
- Stable. Incompatible with strong oxidizing agents. Protect from moisture.
- InChI
- InChI=1S/C20H29N3O2.ClH/c1-4-7-14-25-19-15-17(16-10-8-9-11-18(16)22-19)20(24)21-12-13-23(5-2)6-3;/h8-11,15H,4-7,12-14H2,1-3H3,(H,21,24);1H
- InChIKey
- IVHBBMHQKZBJEU-UHFFFAOYSA-N
- SMILES
- C12C=CC=CC1=NC(OCCCC)=CC=2C(=O)NCCN(CC)CC.Cl
- CAS DataBase Reference
- 61-12-1(CAS DataBase Reference)
MSDS
- Language:English Provider:2-Butoxy-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide monohydrochloride
- Language:English Provider:SigmaAldrich
Dibucaine hydrochloride Usage And Synthesis
Chemical Properties
white powder
Uses
Anesthetic (local).
Uses
Cinchocaine is used as an anaesthetic agent for spinal anaesthesia; a component in rectal medications used in inflammation of the anus and for the symptomatic treatment of hemorrhoids and fissures in the anus; local anesthetic agent.
Uses
Dibucaine HCl is an amide-like quinoline derivative and is one of the most potent and longest acting of the commonly used local anesthetics.
Definition
ChEBI: The monohydrochloride salt of cinchocaine. It is used in creams, ointments and suppositories for temporary relief of pain and itching associated with skin and anorectal conditions.
brand name
Nupercaine (Novartis).
Contact allergens
Dibucaine hydrochloride is an amide group local anesthetic that can induce allergic contact dermatitis.
Safety Profile
Poison by ingestion,subcutaneous, intravenous, intraspinal, parenteral, andintraperitoneal routes. Mutation data reported. A severeeye irritant. A local anesthetic. When heated todecomposition it emits very toxic fumes of HCl and NOx
Dibucaine hydrochloride Preparation Products And Raw materials
Raw materials
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