Cenupatide Chemical Properties

Density 

1.34±0.1 g/cm3(Predicted)

pka

12.99±0.46(Predicted)

form 

Solid

color 

White to off-white

Sequence

Ac-Arg-{Aib}-Arg-{aMePhe}-NH2

Cenupatide Usage And Synthesis

Uses

Cenupatide (UPARANT) is a Urokinase-type plasminogen activator receptor (uPAR) inhibitor. Cenupatide has anti-angiogenic and anti-inflammatory efficacy[1].

References

[1] Filippo Locri, et al. UPARANT is an effective antiangiogenic agent in a mouse model of rubeosis iridis. J Mol Med (Berl). 2019, 97, 9.
[2] Cai Yuan, et al. Development of inhibitors for uPAR: blocking the interaction of uPAR with its partners. Drug Discov Today. 2021, 26, 4. DOI:10.1016/j.drudis.2021.01.016

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