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1,2-Bis(trifluoromethyl)benzene

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1,2-Bis(trifluoromethyl)benzene Basic information

Product Name:
1,2-Bis(trifluoromethyl)benzene
Synonyms:
  • o-Bis(trifluoromethyl)benzene
  • o-Xylene, alpha,alpha,alpha,alpha',alpha',alpha'-hexafluoro-
  • 1,2-BIS(TRIFLUOROMETHYL)BENZENE
  • 1,2-BIS(TRIFLUROMETHYL)BENZENE
  • alpha,alpha,alpha,alpha',alpha',alpha'-Hexafluoro-o-xylene
  • α,α,α,α',α',α'-Hexafluoro-o-xylene
  • 1,2-Bis(trifuoromethyl)benzene
  • 1,2-Bis(trifluoromethyl)benzene>
CAS:
433-95-4
MF:
C8H4F6
MW:
214.11
EINECS:
207-092-3
Mol File:
433-95-4.mol
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1,2-Bis(trifluoromethyl)benzene Chemical Properties

Boiling point:
142 °C
Density 
1.44
refractive index 
1.3920-1.3960
form 
clear liquid
color 
Colorless to Almost colorless
CAS DataBase Reference
433-95-4(CAS DataBase Reference)
NIST Chemistry Reference
Benzene, 1,2-bis(trifluoromethyl)-(433-95-4)
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Safety Information

Hazard Codes 
F
RIDADR 
1993
Hazard Note 
Flammable
HazardClass 
3
PackingGroup 
III
HS Code 
29039990
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1,2-Bis(trifluoromethyl)benzene Usage And Synthesis

Uses

1,2-Bis(trifluoromethyl)benzene is a useful reagent for preparing biphenyls through arylation of electron-deficient arenes with aryl halides. It was also employed to investigate the effect of aromatic trifluoromethylation, fluorination, and methylation on intermolecular n-n interactions. The results can provide insights on interactions between drug molecules and protein receptors.

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