SL0101
SL0101 Basic information
- Product Name:
- SL0101
- Synonyms:
-
- SL-0101-1;SL0101-1;SL-0101;SL 0101;SL0101;SL0101 1
- RSK Inhibitor, SL0101
- 3-[(3,4-Di-O-acetyl-6-deoxy-α-L-Mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
- Kaempferol 3-O-(3'',4''-di-O-acetyl-alpha-L-rhamnopyranoside)
- SL0101
- 2-(4-Hydroxyphenyl)-3-(3-O,4-O-diacetyl-α-L-rhamnopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one
- 2-(4-Hydroxyphenyl)-4-oxo-5,7-dihydroxy-4H-1-benzopyran-3-yl 3-O,4-O-diacetyl-α-L-rhamnopyranoside
- 3-(3-O,4-O-Diacetyl-α-L-rhamnopyranosyloxy)-4',5,7-trihydroxyflavone
- CAS:
- 77307-50-7
- MF:
- C25H24O12
- MW:
- 516.45
- Product Categories:
-
- 13C & 2H Sugars
- Carbohydrates & Derivatives
- Inhibitors
- Mol File:
- 77307-50-7.mol
SL0101 Chemical Properties
- Melting point:
- 128-132°C
- Boiling point:
- 753.0±60.0 °C(Predicted)
- Density
- 1.57±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Acetone (Slightly), Methanol (Slightly)
- form
- Yellow solid
- pka
- 6.20±0.40(Predicted)
- color
- Pale Yellow to Brown
SL0101 Usage And Synthesis
Description
The p90 ribosomal S6 kinases (RSK) 1-
Chemical Properties
Tan Solid
Uses
SL 0101 is a potent and selective inhibitor of p90 Rsk, without inhibiting the function of upstream kinases such as MEK, Raf, or PKC.
Biological Activity
Selective inhibitor of p90 ribosomal S6 kinase (RSK) (IC 50 = 89 nM for RSK2). Does not inhibit upstream kinases such as MEK, Raf and PKC.? Inhibits the growth of MCF-7 human breast cancer cells with no effect on the normal breast cell line.
storage
-20°C
SL0101Supplier
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