(S)-H8-BINAP Chemical Properties

Melting point:

207-208°C

Boiling point:

745.6±60.0 °C(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

form 

Powder

color 

off-white

Safety Information

WGK Germany 

3

(S)-H8-BINAP Usage And Synthesis

Reactions

1. Biaryl bisphosphine ligand. The H8-BINAP ligand, as the ruthenium complex, catalyzes hydrogenation of unsaturated carboxylic acids to a higher ee than does BINAP.
2. The ruthenium catalyzed hydrogenation of aryl propenoic acid to produce the drug Ibuprofen.
3. Rhodium catalyzed asymmetric regioselective 1,4-addition of arylboronic acids to 3-substituted maleimides.
4. Ligand for palladium-catalyzed enantioselective hydrogenation of substituted indoles.
5. Rhodium-catalyzed enantioselective cyclization of γ-alkynylaldehydes with acyl phosphonates.
6. Enantioselective synthesis of axially chiral 1-arylisoquinolines by Rh-catalyzed [2+2+2] cycloaddition.
7. Enantioselective synthesis of 2,3-disubstituted indolines through Bronsted acid/Pd-complex-promoted tandem reactions.

(S)-H8-BINAP(139139-93-8)Related Product Information

• (R)-DTBM-SEGPHOS
• (R)-DM-BINAP
• (R)-DIFLUORPHOS(TM)
• (S)-SunPhos
• (S)-(+)-2,2'-Bis[di(3,5-di-t-butyl-4-methoxyphenyl)phosphino]-6,6'-dimethoxy-1,1'-biphenyl,min.97%
• (R)-(+)-TolBINAP
• (R)-(6,6'-Dimethoxybiphenyl-2,2'-diyl)bis[bis(3,5-di-tert-butyl-4-methoxypheny
• R(+)-2 2'-BIS-(DIPHENYLPHOSPHINO)-6 6'-&
• (S)-(-)-2,2'-Bis[di(3,5-xylyl)phosphino]-1,1'-binaphthyl
• (S)-(-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl
• (R)-SEGPHOS
• (R)-(+)-2,2'-Bis(di-i-propylphosphino)-6,6'-dimethoxy-1,1'-biphenyl,min.97%
• (S)-(-)-5,5'-Bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole,min.98%(S)-SEGPHOS
• (R)-H8-BINAP
• (R)-DIFLUORPHOS(TM)
• (S)-(+)-5,5'-Bis[di(3,5-di-t-butyl-4-methoxyphenyl)phosphino]-4,4'-bi-1,3-benzodioxole,min.98%(S)-DTBM-SEGPHOS
• (S)-(-)-2,2'-BIS(DI-P-TOLYLPHOSPHINO)-1,1'-BINAPHTHYL