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ChemicalBook >  Product Catalog >  Chemical Reagents >  Organic reagents >  Phosphine ligand >  (R)-(6,6'-Dimethoxybiphenyl-2,2'-diyl)bis[bis(3,5-di-tert-butyl-4-methoxypheny

(R)-(6,6'-Dimethoxybiphenyl-2,2'-diyl)bis[bis(3,5-di-tert-butyl-4-methoxypheny

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(R)-(6,6'-Dimethoxybiphenyl-2,2'-diyl)bis[bis(3,5-di-tert-butyl-4-methoxypheny Basic information

Product Name:
(R)-(6,6'-Dimethoxybiphenyl-2,2'-diyl)bis[bis(3,5-di-tert-butyl-4-methoxypheny
Synonyms:
  • (R)-(6,6'-Dimethoxybiphenyl-2,2'-diyl)bis[bis(3,5-di-tert-butyl-4-methoxypheny
  • (R)-(-)-2,2'-Bis[di(3,5-di-t-butyl-4-methoxyphenyl)phosphino]-6,6'-dimethoxy-1,1'-biphenyl,min.97%
  • (R)-(-)-2,2''-BIS[DI(3,5-DI-T-BUTYL-4-METHOXYPHENYL)PHOSPHINO]-6,6''-DIMETHOXY-1,1''-BIPHENYL, MIN. 97%
  • (S)-(6,6μ-Dimethoxybiphenyl-2,2μ-diyl)bis[bis(3,5-di-tert-butyl-4-methoxyphenyl)phosphine]
  • (S)-3,5-t-Bu-4-MeO-MeOBIPHEP, SL-A109-2, (S)-[6,6μ-Dimethoxy(1,1μ-biphenyl)-2,2μ-diyl]bis{bis[3,5-bis(1,1-dimethylethyl)-4-methoxyphenyl]phosphine}
  • (R)-(6,6μ-Dimethoxybiphenyl-2,2μ-diyl)bis[bis(3,5-di-tert-butyl-4-methoxyphenyl)phosphine]
  • (R)-3,5-t-Bu-4-MeO-MeOBIPHEP, SL-A109-1, (R)-[6,6μ-Dimethoxy(1,1μ-biphenyl)-2,2μ-diyl]bis{bis[3,5-bis(1,1-dimethylethyl)-4-methoxyphenyl]phosphine}
  • (R)-(-)-2,2'-Bis[di-(3,5-di-tert-butyl-4-methoxy-phenyl)phosphino]-(diphenylphosphino)-6,6'-dimethoxy-1,1'-biphenyl
CAS:
352655-61-9
MF:
C74H104O6P2
MW:
1151.56
Product Categories:
  • Chiral Phosphine
  • MeOBIPHEP Series
Mol File:
352655-61-9.mol
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(R)-(6,6'-Dimethoxybiphenyl-2,2'-diyl)bis[bis(3,5-di-tert-butyl-4-methoxypheny Chemical Properties

Boiling point:
951.5±65.0 °C(Predicted)
form 
crystal
color 
white
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Safety Information

WGK Germany 
3
HS Code 
29319090
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(R)-(6,6'-Dimethoxybiphenyl-2,2'-diyl)bis[bis(3,5-di-tert-butyl-4-methoxypheny Usage And Synthesis

Reaction

  1. Rh-catalyzed reductive coupling of acetylene to aldehydes and ketones.
  2. Pt-catalyzed intramolecular hydroarylation of unactivated alkenes with indoles.
  3. Enantioselective C-C bond activation of allenyl cyclobutanes.
  4. Enantioselective ring-opening of rac-ethynyl epoxides.
  5. Enantioselective Au-catalyzed allylic alkylation of indoles with alcohols.
  6. Enantioselective Rh-catalyzed conjugate alkynylation with TMS-acetylene.
  7. Enantioselective Rh-catalyzed [3+2] annulation of aromatic ketimines.
  8. Asymmetric Rh-catalyzed Pausan-Khand reaction. 


Chemical Properties

Off-white powder

Uses

Atropisomeric MeOBIPHEP ligands

  • Asymmetrical conjugate addition of arylboronic acids to maleimides and enones catalyzed by rhodium complexes
  • Intramolecular ketone hydroacylation
  • Desymmetrization through enantioselective C-C bond activation and ring expansion of allenyl cyclobutanols
  • Hydroamination of bicyclic alkenes and dienes with anilines
  • 1,4-addition/asymmetric protonation of amino acrylates

General Description

sold in collaboration with Solvias AG

(R)-(6,6'-Dimethoxybiphenyl-2,2'-diyl)bis[bis(3,5-di-tert-butyl-4-methoxyphenySupplier

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