[1-(Ethoxycarbonyl)ethyl]triphenylphosphonium bromide Chemical Properties

Melting point:

152 °C

storage temp. 

Refrigerator (+4°C)

solubility 

Chloroform, Methanol

form 

Solid

color 

Pale Yellow

Water Solubility 

soluble

Sensitive 

Hygroscopic

BRN 

3822244

InChI

InChI=1S/C23H24O2P.BrH/c1-3-25-23(24)19(2)26(20-13-7-4-8-14-20,21-15-9-5-10-16-21)22-17-11-6-12-18-22;/h4-19H,3H2,1-2H3;1H/q+1;/p-1

InChIKey

RSYXORMKBUFAMS-UHFFFAOYSA-M

SMILES

[P+](C1C=CC=CC=1)(C1C=CC=CC=1)(C1C=CC=CC=1)C(C)C(=O)OCC.[Br-]

CAS DataBase Reference

30018-16-7(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-29-22

Safety Statements 

26-36-8-37/39

Hazard Note 

Irritant/Hygroscopic

HS Code 

29310099

MSDS

• Language:English Provider:ALFA

[1-(Ethoxycarbonyl)ethyl]triphenylphosphonium bromide Usage And Synthesis

Chemical Properties

White to off-white powder

Uses

suzuki reaction

Uses

1-Ethoxycarbonylethyl)triphenylphosphonium bromide is an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff. It is widely used as an organophosphine catalyst.

Synthesis

1.0 g of triphenylphosphine was dissolved in 15 mL of ethyl acetate and 0.55 mL of ethyl 2-bromopropionate was added to this solution. The reaction mixture was stirred at room temperature for 24 hours. Upon completion of the reaction, the bulk of the resulting white solid product was collected by diafiltration. The solids were washed with ethyl acetate to give a final 1.35 g of white solid product ethoxycarbonyl ethyltriphenylphosphonium bromide in 80.5% yield.

References

[1] European Journal of Organic Chemistry, 2016, vol. 2016, # 12, p. 2110 - 2114
[2] Chemistry - A European Journal, 2015, vol. 21, # 20, p. 7408 - 7412
[3] Tetrahedron, 2010, vol. 66, # 26, p. 4745 - 4759
[4] Journal of Organic Chemistry, 1984, vol. 49, # 22, p. 4293 - 4295
[5] Patent: CN103864753, 2016, B. Location in patent: Paragraph 0087; 0110-0111

[1-(Ethoxycarbonyl)ethyl]triphenylphosphonium bromide(30018-16-7)Related Product Information

• Ethyl acetate
• Ethyltriphenylphosphonium bromide
• Triphenylphosphine oxide
• 2-Ethoxyethanol
• 2-Ethoxyphenol
• Ethylparaben
• Ethoxyquin
• Clidinium bromide
• Sodium bromate
• Ethyltriphenylphosphonium acetate
• Diphenylphosphine
• Ethanol
• Ethidium bromide
• Chlorodiphenylphosphine
• Tetraethylammonium bromide
• DIETHOXYMETHANE
• Diethoxymethyl acetate
• Ethyl acrylate