Ethyltriphenylphosphonium bromide Chemical Properties

Melting point:

203-205 °C(lit.)

Boiling point:

240℃[at 101 325 Pa]

Density 

1.38[at 20℃]

vapor pressure 

0-0.1Pa at 20-25℃

Flash point:

200 °C

storage temp. 

Inert atmosphere,Room Temperature

solubility 

174g/l soluble

form 

Crystalline Powder

color 

White to off-white

Water Solubility 

120 g/L (23 ºC)

Sensitive 

Hygroscopic

BRN 

3599630

InChIKey

JHYNXXDQQHTCHJ-UHFFFAOYSA-M

LogP

-0.69--0.446 at 35℃

CAS DataBase Reference

1530-32-1(CAS DataBase Reference)

EPA Substance Registry System

Phosphonium, ethyltriphenyl-, bromide (1530-32-1)

Safety Information

Hazard Codes 

Xn,N,Xi

Risk Statements 

22-51/53-36/37/38-21/22

Safety Statements 

61-36/37/39-26-36

RIDADR 

UN 3077 9/PG 3

WGK Germany 

2

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29310095

MSDS

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Ethyltriphenylphosphonium bromide Usage And Synthesis

Chemical Properties

White to off-white crystalline powder

Uses

suzuki reaction

Uses

Ethyltriphenylphosphonium Bromide is used as a wittig reagent. Ethyltriphenylphosphonium Bromide and other phosphonium salts show antiviral activity.

Uses

Ethyltriphenylphosphonium Bromide (ETPB) is a phase transfer catalyst, used to accelerate the cure of phenolic-based epoxy resins, certain fluoroelastomer resins and thermosetting powder coatings. It is also used as catalysts in the synthesis of certain organic compounds and as a pharmaceutical intermediate.

1. Ethyltriphenylphosphonium bromide acts as a reactant in the synthesis of D-amino acids from L-cysteine-derived thiazolidines, Leiodolide A through aldol reactions and Horner-Wadsworth-Emmons olefination.
2. It is also used in the preparation of cycloalkanoindolines through diastereoselective intramolecular inimo-ene reactions.
3. it is used as a reagent in solid-state metathesis polycondensation to prepare alkyl-dipropenylthiophene monomers.
4. Mizoroki-Heck cyclization and cascading Tsuji-Trost cyclization reactions.

Uses

PTC catalyst

Flammability and Explosibility

Not classified

Purification Methods

Recrystallise it from H2O and dry it in high vacuum at 100o. IR has bands at 1449, 1431 and 997cm-1 . [Wittig & Wittenberg Justus Liebigs Ann Chem 606 1 1957, Bergmann & Dusza J Org Chem 23 1245 1958, Beilstein 16 IV 982.]

Ethyltriphenylphosphonium bromide(1530-32-1)Related Product Information

• DICHLOROTRIPHENYLPHOSPHORANE
• Triphenylphosphine hydrobromide
• Methyltriphenylphosphonium bromide
• Ethylmagnesium bromide
• PHENYLMAGNESIUM BROMIDE
• Tris(triphenylphosphine)rhodiu
• Vecuronium bromide
• Tetraphenylphosphonium bromide
• Dimidium bromide
• Tetraethylammonium bromide
• Ethyltriphenylphosphonium iodide
• Triphenylphosphine
• Allyl bromide
• Rocuronium bromide
• Triphenylphosphine oxide
• Sodium bromate
• Ethidium bromide
• Ethyltriphenylphosphonium acetate