Ethyltriphenylphosphonium bromide Chemical Properties

Melting point:

203-205 °C(lit.)

Boiling point:

240℃[at 101 325 Pa]

Density 

1.38[at 20℃]

vapor pressure 

0-0.1Pa at 20-25℃

Flash point:

200 °C

storage temp. 

Inert atmosphere,Room Temperature

solubility 

174g/l soluble

form 

Crystalline Powder

color 

White to off-white

Water Solubility 

120 g/L (23 ºC)

Sensitive 

Hygroscopic

BRN 

3599630

InChIKey

JHYNXXDQQHTCHJ-UHFFFAOYSA-M

LogP

-0.69--0.446 at 35℃

CAS DataBase Reference

1530-32-1(CAS DataBase Reference)

EPA Substance Registry System

Phosphonium, ethyltriphenyl-, bromide (1530-32-1)

Safety Information

Hazard Codes 

Xn,N,Xi

Risk Statements 

22-51/53-36/37/38-21/22

Safety Statements 

61-36/37/39-26-36

RIDADR 

UN 3077 9/PG 3

WGK Germany 

2

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29310095

MSDS

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Ethyltriphenylphosphonium bromide Usage And Synthesis

Chemical Properties

White to off-white crystalline powder

Uses

suzuki reaction

Uses

Ethyltriphenylphosphonium Bromide is used as a wittig reagent. Ethyltriphenylphosphonium Bromide and other phosphonium salts show antiviral activity.

Uses

Ethyltriphenylphosphonium Bromide (ETPB) is a phase transfer catalyst, used to accelerate the cure of phenolic-based epoxy resins, certain fluoroelastomer resins and thermosetting powder coatings. It is also used as catalysts in the synthesis of certain organic compounds and as a pharmaceutical intermediate.

1. Ethyltriphenylphosphonium bromide acts as a reactant in the synthesis of D-amino acids from L-cysteine-derived thiazolidines, Leiodolide A through aldol reactions and Horner-Wadsworth-Emmons olefination.
2. It is also used in the preparation of cycloalkanoindolines through diastereoselective intramolecular inimo-ene reactions.
3. it is used as a reagent in solid-state metathesis polycondensation to prepare alkyl-dipropenylthiophene monomers.
4. Mizoroki-Heck cyclization and cascading Tsuji-Trost cyclization reactions.

Uses

PTC catalyst

Flammability and Explosibility

Not classified

reaction suitability

reaction type: C-C Bond Formation

Purification Methods

Recrystallise it from H2O and dry it in high vacuum at 100o. IR has bands at 1449, 1431 and 997cm-1 . [Wittig & Wittenberg Justus Liebigs Ann Chem 606 1 1957, Bergmann & Dusza J Org Chem 23 1245 1958, Beilstein 16 IV 982.]

Ethyltriphenylphosphonium bromide(1530-32-1)Related Product Information

• DICHLOROTRIPHENYLPHOSPHORANE
• Triphenylphosphine hydrobromide
• Methyltriphenylphosphonium bromide
• Ethylmagnesium bromide
• PHENYLMAGNESIUM BROMIDE
• Tris(triphenylphosphine)rhodiu
• Vecuronium bromide
• Tetraphenylphosphonium bromide
• Dimidium bromide
• Tetraethylammonium bromide
• Ethyltriphenylphosphonium iodide
• Triphenylphosphine
• Allyl bromide
• Rocuronium bromide
• Triphenylphosphine oxide
• Sodium bromate
• Ethidium bromide
• Ethyltriphenylphosphonium acetate