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CYCLO(-PHE-PRO)

Basic information Safety Supplier Related

CYCLO(-PHE-PRO) Basic information

Product Name:
CYCLO(-PHE-PRO)
Synonyms:
  • (3S-trans)-3-benzylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione
  • (3S,8aS)-3-Benzyl-6,7,8,8aα-tetrahydropyrrolo[1,2-a]pyrazine-1,4(2H,3H)-dione
  • (3S,8aS)-3β-Benzyl-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazine-1,4(2H,3H)-dione
  • (3S,8aα)-3β-Benzyloctahydropyrrolo[1,2-a]pyrazine-1,4-dione
  • Cyclo(L-Phe-L-Pro-)
  • Cyclo(Pro-Phe-)
  • (3S)-2,3,6,7,8,8aβ-Hexahydro-3β-(phenylmethyl)pyrrolo[1,2-a]pyrazine-1,4-dione
  • Cyclo(D-Pro-L-Phe-)
CAS:
3705-26-8
MF:
C14H16N2O2
MW:
244.29
EINECS:
223-047-0
Mol File:
3705-26-8.mol
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CYCLO(-PHE-PRO) Chemical Properties

Melting point:
146-148 °C
Boiling point:
509.5±39.0 °C(Predicted)
Density 
1.26±0.1 g/cm3(Predicted)
storage temp. 
-15°C
pka
13.21±0.40(Predicted)
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CYCLO(-PHE-PRO) Usage And Synthesis

Chemical Properties

White powder

Uses

Cyclo(L-Phe-L-Pro) is a diketopiperazine formed by the fusion of phenylalanine and proline, reported as a secondary metabolite of fungi and bacteria. In Pseudomonas aeruginosa, cyclo(L-Phe-L-Pro) is capable of activating N-acylhomoserine lactones (AHLs). Cyclo(L-Phe-L-Pro) is also capable of activating or antagonizing other LuxR-based quorum-sensing systems. While the mode of action of cyclo(L-Phe-L-Pro) is not known, its activity suggests the existence of cross talk among bacterial signalling systems.

CYCLO(-PHE-PRO)Supplier

GL Biochem (Shanghai) Ltd
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86-21-61263452 (tel), 86-13641803416(mobile)
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ymbetter@glbiochem.com
Chemsky(shanghai)International Co.,Ltd.
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021-50135380
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shchemsky@sina.com
BioBioPha Co., Ltd.
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0871-65217109-
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ChemStrong Scientific Co.,Ltd
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Finetech Industry Limited
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