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2-Methylpiperazine

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2-Methylpiperazine Basic information

Product Name:
2-Methylpiperazine
Synonyms:
  • 2-methyl-piperazin
  • MP
  • 2-METHYLDIETHYLENEDIAMINE
  • (+/-)-2-METHYLPIPERAZINE
  • 2-METHYLPIPERAZINE
  • 2MPRZ
  • 2-METHYLPIPERAZINE/LOMEFLOXCIN
  • 2-Methylpiperazine ,99%
CAS:
109-07-9
MF:
C5H12N2
MW:
100.16
EINECS:
203-644-2
Product Categories:
  • Building Blocks
  • C4 to C8
  • Building Blocks
  • Heterocyclic Building Blocks
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Piperidines, Piperidones, Piperazines
  • Piperaizine
  • Piperazine derivates
  • Piperazines
  • OLED
Mol File:
109-07-9.mol
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2-Methylpiperazine Chemical Properties

Melting point:
61-63 °C (lit.)
Boiling point:
155 °C/763 mmHg (lit.)
Density 
0.817 g/cm
refractive index 
1.4378 (estimate)
Flash point:
149 °F
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
435g/l
pka
pK1:5.62(+2);pK2:9.60(+1) (25°C)
form 
Crystalline Powder, Crystals and/or Chunks
color 
White to yellow
PH
11-12 (50g/l, H2O)
Water Solubility 
78 g/100 mL (25 ºC)
Sensitive 
Air Sensitive & Hygroscopic
BRN 
383566
InChIKey
JOMNTHCQHJPVAZ-UHFFFAOYSA-N
CAS DataBase Reference
109-07-9(CAS DataBase Reference)
NIST Chemistry Reference
Piperazine, 2-methyl-(109-07-9)
EPA Substance Registry System
Piperazine, 2-methyl- (109-07-9)
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Safety Information

Hazard Codes 
F,Xi
Risk Statements 
11-36/37/38
Safety Statements 
16-26-36/37/39-36
RIDADR 
UN 1325 4.1/PG 2
WGK Germany 
2
RTECS 
TM1225020
10
TSCA 
Yes
HazardClass 
4.1
PackingGroup 
III
HS Code 
29339900

MSDS

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2-Methylpiperazine Usage And Synthesis

Chemical Properties

white to yellow crystalline powder and chunks

Uses

2-Methylpiperazine is used as a reagent in the design, synthesis and biological evaluation of diaminoquinazolines as b-catenine/Tcell transcription factor 4 (Tcf4) pathway inhibitor.

Purification Methods

Purify it by zone melting and by distillation. It is hygroscopic. The picrate has m 275-276o. [Beilstein 23 II 16, 23 III/IV 393, 23/3 V 267.]

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