4,4'-Difluorobenzhydrylpiperazine Chemical Properties

Melting point:

88-92 °C(lit.)

Boiling point:

130 °C

Density 

1.1462 (estimate)

vapor pressure 

0.001-0.003Pa at 20-25℃

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

soluble in Methanol,Toluene

pka

9.00±0.10(Predicted)

form 

Crystalline Powder

color 

White to yellow

Water Solubility 

0.34 g/L (20 ºC)

BRN 

620754

Stability:

Hygroscopic

LogP

3.3-3.5 at pH7-11

CAS DataBase Reference

27469-60-9(CAS DataBase Reference)

Safety Information

Hazard Codes 

T

Risk Statements 

25-36/37/38

Safety Statements 

26-45-36/37/39

RIDADR 

UN 2811 6.1/PG 3

WGK Germany 

3

F 

10-34

Hazard Note 

Toxic

HazardClass 

IRRITANT

HazardClass 

6.1

PackingGroup 

III

HS Code 

29335990

MSDS

• Language:English Provider:1-(4,4'-Difluorobenzhydryl)piperazine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

4,4'-Difluorobenzhydrylpiperazine Usage And Synthesis

Chemical Properties

white to yellow crystalline powder

Uses

1-Bis(4-fluorophenyl)methyl piperazine may be used to synthesize 1-[bis(4-fluorophenyl)methyl]-4-[3-[(N-ethoxycarbonyl-N-phenyl)amino]-2-hydroxypropyl]piperazine and (R, S) 3-[4-(bis(4-fluorophenyl)methyl)piperazin-1-yl]dihydrofuran-2(3H)-one.

General Description

1-Bis(4-fluorophenyl)methyl piperazine is formed during the synthesis of flunarizine. Its crystals exhibits monoclinic crystal system and space group P2₁/c.

4,4'-Difluorobenzhydrylpiperazine(27469-60-9)Related Product Information

• 3,4-Difluorobenzoic acid
• 1-Methylpiperazine
• 1,3-Difluorobenzene
• Florfenicol
• 2,4-Difluorobenzoic acid
• 1,2-Difluorobenzene
• Piperazine
• Almitrine dimesylate
• Lomerizine hydrochloride
• ALMITRINE
• Lomerizine
• Carsatrin
• Flunarizine dihydrochloride
• Flunarizine
• Efletirizine
• 1-BENZHYDRYLPIPERAZINE
• 4-{4-[Bis(4-fluorophenyl)methyl]piperazinyl}benzyl alcohol
• 1-[BIS(4-FLUOROPHENYL)METHYL]-4-(4-NITROPHENYL)PIPERAZINE