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oxoglaucine

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oxoglaucine Basic information

Product Name:
oxoglaucine
Synonyms:
  • oxoglaucine
  • 1,2,9,10-Tetramethoxy-7H-dibenzo[de,g]quinolin-7-one
  • O-Methylatheroline
  • 7H-Dibenzo[de,g]quinolin-7-one, 1,2,9,10-tetramethoxy-
  • oxoglaucine USP/EP/BP
CAS:
5574-24-3
MF:
C20H17NO5
MW:
351.35
Mol File:
5574-24-3.mol
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oxoglaucine Chemical Properties

Melting point:
227-229℃ (chloroform methanol )
Boiling point:
577.9±50.0 °C(Predicted)
Density 
1.310±0.06 g/cm3 (20 ºC 760 Torr)
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
pka
1.93±0.20(Predicted)
InChI
InChI=1S/C20H17NO5/c1-23-13-8-11-12(9-14(13)24-2)19(22)18-16-10(5-6-21-18)7-15(25-3)20(26-4)17(11)16/h5-9H,1-4H3
InChIKey
ZYKCETVKVRJFGD-UHFFFAOYSA-N
SMILES
N1C2=C3C(=C(OC)C(OC)=CC3=CC=1)C1=CC(OC)=C(OC)C=C1C2=O
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oxoglaucine Usage And Synthesis

Description

An alkaloid isolated from Annona purpurea, O-methylatheroline contains four methoxyl groups in the molecule. Physiologically, it has been found to be cytotoxic to 9-KB experimental tumours.

Chemical Properties

Soluble in organic solvents such as methanol, ethanol, and DMSO.

Definition

ChEBI: Oxoglaucine is an isoquinoline alkaloid.

References

Sonnet, Jacobson,J. Pharm. Sci., 60, 1254 (1971)

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