Basic information Safety Supplier Related

2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide

Basic information Safety Supplier Related

2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide Basic information

Product Name:
2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide
Synonyms:
  • 2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide
  • AcetaMide, 2-cyano-N-[4-(trifluoroMethyl)phenyl]-
  • Leflunomide Impurity H
  • Leflunomide EP Impurity H
  • Leflunomide Impurity 8(Leflunomide EP Impurity H)
  • 2-Cyano-N-[4-(trifluoromethyl)phenyl]acetamide
  • 2-Cyano-N-[4-(trifluoromethyl)pheny
  • 2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide USP/EP/BP
CAS:
24522-30-3
MF:
C10H7F3N2O
MW:
228.17
Mol File:
24522-30-3.mol
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2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide Chemical Properties

Melting point:
145-147℃
Boiling point:
386.3±42.0 °C(Predicted)
Density 
1.375±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
4.63±0.10(Predicted)
color 
White to Off-White
Stability:
Hygroscopic
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Safety Information

HS Code 
2924297099
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2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide Usage And Synthesis

Uses

2-Cyano-N-[4-(trifluoromethyl)phenyl]acetamide (Leflunomide EP Impurity H) is used to prepare aminothiophene carboxylates and carboxamides as adenosine A1 receptor allosteric enhancers. It is also used to synthesize (1,2,3-triazol-4-yl)benzenamines as inhibitors against VEGF receptors 1 and 2.

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