2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide
2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide Basic information
- Product Name:
- 2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide
- Synonyms:
-
- 2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide
- AcetaMide, 2-cyano-N-[4-(trifluoroMethyl)phenyl]-
- Leflunomide Impurity H
- Leflunomide EP Impurity H
- Leflunomide Impurity 8(Leflunomide EP Impurity H)
- 2-Cyano-N-[4-(trifluoromethyl)phenyl]acetamide
- 2-Cyano-N-[4-(trifluoromethyl)pheny
- 2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide USP/EP/BP
- CAS:
- 24522-30-3
- MF:
- C10H7F3N2O
- MW:
- 228.17
- Mol File:
- 24522-30-3.mol
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2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide Chemical Properties
- Melting point:
- 145-147℃
- Boiling point:
- 386.3±42.0 °C(Predicted)
- Density
- 1.375±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 4.63±0.10(Predicted)
- color
- White to Off-White
- Stability:
- Hygroscopic
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2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide Usage And Synthesis
Uses
2-Cyano-N-[4-(trifluoromethyl)phenyl]acetamide (Leflunomide EP Impurity H) is used to prepare aminothiophene carboxylates and carboxamides as adenosine A1 receptor allosteric enhancers. It is also used to synthesize (1,2,3-triazol-4-yl)benzenamines as inhibitors against VEGF receptors 1 and 2.
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