ALPHA-METHYLBENZYL ALCOHOL Chemical Properties

Melting point:

19-20 °C(lit.)

Boiling point:

204 °C745 mm Hg(lit.)

Density 

1.012 g/mL at 25 °C(lit.)

vapor density 

4.21 (vs air)

vapor pressure 

0.1 mm Hg ( 20 °C)

refractive index 

n20/D 1.527(lit.)

Flash point:

185 °F

Dielectric constant

7.6（90℃）

CAS DataBase Reference

13323-81-4(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-38-41

Safety Statements 

26-39

RIDADR 

UN 2937 6.1/PG 3

WGK Germany 

1

RTECS 

DO9275000

HazardClass 

6.1

PackingGroup 

III

Toxicity

The acute oral LD₅₀ in rats was reported as 400 mg/kg (Smyth & Carpenter, 1944). The acute dermal LD₅₀ value in rabbits exceeded 2.5 g/kg (Moreno, 1973).

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

ALPHA-METHYLBENZYL ALCOHOL Usage And Synthesis

Chemical Properties

Colorless liquid

Occurrence

Has apparently not been reported to occur in nature.

Preparation

By hydrogenation or reduction of acetophenone; or from methyl magnesium chloride plus benzaldehyde by a Grignard-type reaction (Bedoukian, 1967).

Definition

ChEBI: 1-phenylethanol is an aromatic alcohol that is ethanol substituted by a phenyl group at position 1. It has a role as a mouse metabolite.

Metabolism

Styrallyl alcohol is converted in rabbits into hippuric acid and methylphenylcarbinyl glucuronide, both optical forms of the carbinol behaving similarly. A small proportion (1-2%) is excreted as mandelic acid (Wjlliams, 1959).

Purification Methods

Purify the alcohol via its hydrogen phthalate. [See Houssa & Kenyon J Chem Soc 2260 1930.] Shake it with a solution of ferrous sulfate, and th

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