Sontuzumab Chemical Properties

form 

Liquid

color 

Colorless to light yellow

Sontuzumab Usage And Synthesis

Uses

Sontuzumab (AS1402) is a humanizedised IgG1κ MUC1 specific monoclonal antibody. Sontuzumab binds the extracellular MUC1 peptide sequence PDTR with a Kd of ~1 nM. Sontuzumab can be used for the research of breast cancer[1].

References

[1] Pegram MD, et al. Phase I dose escalation pharmacokinetic assessment of intravenous humanized anti-MUC1 antibody AS1402 in patients with advanced breast cancer. Breast Cancer Res. 2009;11(5):R73. DOI:10.1186/bcr2409
[2] Snijdewint FG, et al. Antibody-dependent cell-mediated cytotoxicity can be induced by MUC1 peptide vaccination of breast cancer patients. Int J Cancer. 2001 Jul 1;93(1):97-106. DOI:10.1002/ijc.1286

Sontuzumab(372075-37-1)Related Product Information

• Sontuzumab
• Rituximab
• Atezolizumab
• Certolizumab
• Vedolizumab
• Balstilimab
• Naratuximab
• Relatlimab
• Zilovertamab
• Domagrozumab