Atorvastatin Cyclic (Fluorophenyl) Impurity Chemical Properties

Melting point:

157-161°C

Boiling point:

785.8±60.0 °C(Predicted)

Density 

1.42±0.1 g/cm3(Predicted)

storage temp. 

-20°C Freezer

solubility 

Methanol (Slightly), Water (Slightly)

form 

Solid

pka

4.35±0.10(Predicted)

color 

White to Off-White

Stability:

Hygroscopic

InChIKey

MVZMCOIMLLJPJD-UHFFFAOYSA-N

SMILES

C(C12C(N3CCC(OC3(C3C=CC(=CC=3)F)C1(C1C=CC=CC=1)O2)CC(O)CC(=O)O)(O)C(C)C)(=O)NC1C=CC=CC=1

Atorvastatin Cyclic (Fluorophenyl) Impurity Usage And Synthesis

Chemical Properties

White to Off-White Solid

Uses

1b-(4-Fluorophenyl)hexahydro-β,7-dihydroxy-7-(1-methylethyl)-1a-phenyl-7a-[(phenylamino)carbonyl]-3H-oxireno[3,4]pyrrolo[2,1-b][1,3]oxazine-3-butanoic Acid is an analyte in the simultaneous quantitative determination of metoprolol, atorvastatin and ramipril.

Uses

A photodegadation product of Atorvastatin (a cyclic impurity of Atorvastatin).

Atorvastatin Cyclic (Fluorophenyl) Impurity(873950-18-6)Related Product Information

• tert-Butyl (4R,6R)-2-[[[6-(2-4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate
• Atorvastatin lactone
• Atorvastatin calcium
• Atorvastatin Epoxy Tetrahydrofuran IMpurity
• 3-Oxo Atorvastatin
• Atorvastatin Amlodipine Dimer
• 3S, 5S enantioMer of Atorvastatin CalciuM
• Atorvastatin Related Compound A
• Atorvastatin tert-Butyl Ester
• Defluoro Atorvastatin intermediate 1
• Difluoro Atorvastatin Acetonide tert-Butyl Ester
• 2,3-Dehydroxy Atorvastatin Sodium Salt
• 3S,5R isoMer, or (3S,5R)-7-[3-(phenylcarbaMoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calciuM salt
• Atorvastatin Methyl Ester
• Atorvastatin Related Compound D (20 mg) (Epoxide impurity, or 3-(4-Fluorobenzoyl)-2-isobutyryl-3-phenyl-oxirane-2- carboxylic acid phenylamide)
• Atorvastatin A8 enantiomer
• Atorvastatin Dehydro Lactone
• Atorvastatin lactam lactone