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Atorvastatin lactone

Basic information Safety Supplier Related

Atorvastatin lactone Basic information

Product Name:
Atorvastatin lactone
Synonyms:
  • 1-[2-[[(2R)-Tetrahydro-4β-hydroxy-6-oxo-2H-pyran]-2α-yl]ethyl]-5-(4-fluorophenyl)-2-isopropyl-4,N-diphenyl-1H-pyrrole-3-carboxamide
  • Atorvastatin EPIMp H (USP RCH)
  • Atorvastatin EP IMpurity H
  • Atorvastatin Related Compound H (20 mg) (5-(4-Fluorophenyl)-1-{2-[(2R, 4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-2-isopropyl-N,4-diphenyl-1H-pyrrole-3-carboxamide)
  • Diepoxide Atorvastatin Lactone Diepoxide
  • Atorvastatin Calcium Impurity D
  • Atorvastatin Impurity H
  • (RS) Atorvastatin Lactone
CAS:
125995-03-1
MF:
C33H33FN2O4
MW:
540.62
Product Categories:
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
Mol File:
125995-03-1.mol
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Atorvastatin lactone Chemical Properties

Melting point:
103-106°C
alpha 
D +26.05° (c = 1 in chloroform)
Boiling point:
674.8±55.0 °C(Predicted)
Density 
1.24±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka
13.39±0.40(Predicted)
form 
Solid
color 
White to Light Yellow
Merck 
14,864
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Safety Information

HS Code 
2933.99.7500
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Atorvastatin lactone Usage And Synthesis

Chemical Properties

Slightly Yellow Solid

Uses

Atorvastatin intermediate as inhibitor of MAP kinase and/or HMG-CoA reductase for the treatment of inflammation

Uses

Atorvastatin Lactone (Atorvastatin EP Impurity H) is an intermediate of Atorvastatin, a inhibitor of MAP kinase and/or HMG-CoA reductase for the treatment of inflammation.

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