Atorvastatin lactone

Product Name: Atorvastatin lactone
CAS No.: 125995-03-1
Chemical Name: Atorvastatin lactone
Synonyms: 5-(4-Fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide;PD-130694;ATORVASTATIN LACTONE;Atorvastatin USP RC H;Atorvastatin calcium-6;Atorvastatin d-Lactone;Atorvastatin Impurity H;LACTONE IMPURITY(IMP-H);(RS) Atorvastatin Lactone;Atorvastatin EP IMpurity H
CBNumber: CB4313438
Molecular Formula: C33H33FN2O4
Formula Weight: 540.62
MOL File: 125995-03-1.mol

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Atorvastatin lactone Property

Melting point:: 103-106°C
alpha: D +26.05° (c = 1 in chloroform)
Boiling point:: 674.8±55.0 °C(Predicted)
Density: 1.24±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka: 13.39±0.40(Predicted)
form: Solid
color: White to Light Yellow
Merck: 14,864

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Safety

HS Code: 2933.99.7500

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 1044582
Product name: Atorvastatin Related Compound H
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 20MG
Price: $1380
Updated: 2024/03/01

TCI Chemical

Product number: A3114
Product name: Atorvastatin Lactone
Purity: >95.0%(HPLC)
Packaging: 25mg
Price: $122
Updated: 2024/03/01

TCI Chemical

Product number: A3114
Product name: Atorvastatin Lactone
Purity: >95.0%(HPLC)
Packaging: 100mg
Price: $362
Updated: 2024/03/01

Cayman Chemical

Product number: 20951
Product name: Atorvastatin lactone
Purity: ≥95%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 20951
Product name: Atorvastatin lactone
Purity: ≥95%
Packaging: 5mg
Price: $116
Updated: 2024/03/01

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Atorvastatin lactone Chemical Properties,Usage,Production

Chemical Properties

Slightly Yellow Solid

Uses

Atorvastatin intermediate as inhibitor of MAP kinase and/or HMG-CoA reductase for the treatment of inflammation

Uses

Atorvastatin Lactone (Atorvastatin EP Impurity H) is an intermediate of Atorvastatin, a inhibitor of MAP kinase and/or HMG-CoA reductase for the treatment of inflammation.

Atorvastatin lactone Preparation Products And Raw materials

Raw materials

Preparation Products

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Atorvastatin lactone Suppliers

Americas 1 Canada 3 China 148 Europe 1 India 21 Japan 1 United Kingdom 2 United States 17 Global 194

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94838
Advantage: 76

JIANGXI AIFEIMU TECHNOLOGY CO.,LTD

Tel: 570-6040289 13735087952
Fax: +86-570-6259526
Email: sales@afmpharm.com
Country: China
ProdList: 96
Advantage: 61

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: zhangsn@titansci.com
Country: China
ProdList: 14113
Advantage: 59

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 17988
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
Advantage: 50

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14059
Advantage: 65

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-4000505016 13380397412
Fax: 0755 28094224
Email: 3001272453@qq.com
Country: China
ProdList: 4978
Advantage: 50

Beijing Comparison Pharmaceutical Technology Co., Ltd

Tel: 010-52878169 15701683040
Email: sales@bjcomparison.com
Country: China
ProdList: 4678
Advantage: 58

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28398
Advantage: 80

TCI Europe

Tel: 320-37350700
Fax: +32 (0)37350701
Email: sales@tcieurope.eu
Country: Europe
ProdList: 23680
Advantage: 75

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View Lastest Price from Atorvastatin lactone manufacturers

Guangzhou PI PI BIOTECH INC

Product: Atorvastatin Impurity H(EP) 125995-03-1
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 90%+
Supply Ability: 10g
Release date: 2020-06-04

Guangzhou PI PI BIOTECH INC

Product: Atorvastatin Impurity E Intermediate
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 90%+
Supply Ability: 10g
Release date: 2020-06-04

Hangzhou ICH Biofarm Co., Ltd

Product: 5-(4-fluorophenyl)-2-(1-methyl-ethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro- hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide 125995-03-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500
Release date: 2023-07-06

125995-03-1, Atorvastatin lactoneRelated Search:

Phenyl salicylate Diphenyl ether Polyvinylpyrrolidone Atorvastatin calcium Isopropyl alcohol N-Methyl-2-pyrrolidone Pyrrolidine PHENYL VALERATE ISOPROPYL LAURATE N-Vinyl-2-pyrrolidone TRIOXSALEN Atorvastatin tert-Butyl (4R,6R)-2-[[[6-(2-4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate Defluoro Atorvastatin Atorvastatin Impurity 40 PHENYL RESIN Phenylacetic acid 3S,5R isoMer, or (3S,5R)-7-[3-(phenylcarbaMoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calciuM salt

1-[2-[[(2R)-Tetrahydro-4β-hydroxy-6-oxo-2H-pyran]-2α-yl]ethyl]-5-(4-fluorophenyl)-2-isopropyl-4,N-diphenyl-1H-pyrrole-3-carboxamide

Atorvastatin EPIMp H (USP RCH)

Atorvastatin EP IMpurity H

Atorvastatin Related Compound H (20 mg) (5-(4-Fluorophenyl)-1-{2-[(2R, 4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-2-isopropyl-N,4-diphenyl-1H-pyrrole-3-carboxamide)

Diepoxide Atorvastatin Lactone Diepoxide

Atorvastatin Calcium Impurity D

Atorvastatin Impurity H

(RS) Atorvastatin Lactone

ATORVASTATIN LACTONE

Atorvastatin lactone (EP impurity H)

(4R,6R)-6-[2-[2-(4-flfluorophenyl)-5-(1-methylethyl)-3- phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]ethyl]-4- hydroxytetrahydro-2H-pyran-2-one

Atorvastatin Impurity H(EP)

Atorvastatin USP RC H

Atorvastatin EP Impurity H (USP RC H)Ator. Lacton

Atorvastatin impurity 9/Atorvastatin EP Impurity H/Atorvastatin Lactone/5-(4-fluorophenyl)-2-(1-methyl-ethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro- hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide

Atorvastatin calcium-6

5-(4-fluorophenyl)-1-(2-((2R,4R)

Atorvastatin Calcium Hydrate impurity H

Atorvastatin EP Impurity H (Atorvastatin Lactone)

5-(4-Fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide

Atorvastatin d-Lactone

(4R,6R)-6-{2-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl}-4-hydroxytetrahydro-2H-pyran-2-one

5-(4-fluorophenyl)-1-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-N,4-diphenyl-2-propan-2-ylpyrrole-3-carboxamide

(3R,5R)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-yl]-3,5-dihydroxyheptanoic acid 1,5-lactone

(4R,6R)-6-[2-[2-(4-Fluorophenyl)-5-

Atorvastatin Lactone (Atorvastatin EP Impurity H)

PD-130694

1H-Pyrrole-3-carboxamide, 5-(4-fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-

1-[2-[[(2R)-Tetrahydro-4β-hydroxy-6-oxo-2H-pyran]-2α-yl]ethyl]-5-(4-fluorophenyl)-2-isopropyl-4,N-diphenyl-1H-pyrrole-3-carboxamide

Atorvastatin lactone ( imp H)

USP Atorvastatin Related Compound H

Atorvastatin EP Impurity H/ Atorvastatin Related Compound H (Atorvastatin Lactone)

Atorvastatin D5 LactoneQ: What is Atorvastatin D5 Lactone Q: What is the CAS Number of Atorvastatin D5 Lactone Q: What is the storage condition of Atorvastatin D5 Lactone Q: What are the applications of Atorvastatin D5 Lactone

Atorvastatin LactoneQ: What is Atorvastatin Lactone Q: What is the CAS Number of Atorvastatin Lactone Q: What is the storage condition of Atorvastatin Lactone Q: What are the applications of Atorvastatin Lactone

Atorvastatin Related Compound H (1044582)Q: What is Atorvastatin Related Compound H (1044582) Q: What is the CAS Number of Atorvastatin Related Compound H (1044582)

AtorvastatinEPImpurityH-d5

Atorvastatin USP Related Compound H

Atorvastatin Calcium Trihydrate EP Impurity H

LACTONE IMPURITY(IMP-H)

Atorvastatin Calcium Trihydrate Impurity H

Atorvastatin calcium impurity H

Atorvastatin EP Impurity H (Atorvastatin USP Related Compound H, Atorvastatin Lactone)

125995-03-1

C33H33FN2O4

Inhibitors

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals