5-alpha-Hydroxy- Laxogenin Chemical Properties

Melting point:

247-250 °C

Boiling point:

578.4±50.0 °C(Predicted)

Density 

1.21±0.1 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMF: 15 mg/ml; DMSO: 10 mg/ml

form 

A solid

pka

12.62±0.70(Predicted)

InChI

InChI=1/C27H42O5/c1-15-5-10-27(31-14-15)16(2)23-21(32-27)12-20-18-11-22(29)26(30)13-17(28)6-9-25(26,4)19(18)7-8-24(20,23)3/h15-21,23,28,30H,5-14H2,1-4H3/t15-,16+,17+,18?,19?,20?,21?,23?,24+,25-,26+,27?/s3

InChIKey

HCRGPOQBVFMZFY-YPAZECSTNA-N

SMILES

C1C[C@]2(C)C3CC[C@]4(C)C5[C@H](C)C6(OC[C@H](C)CC6)OC5CC4C3CC(=O)[C@@]2(O)C[C@H]1O |&1:2,7,10,15,27,30,r|

5-alpha-Hydroxy- Laxogenin Usage And Synthesis

Uses

5α-Hydroxy laxogenin is a synthetic derivative of a naturally occurring spirostane-type steroid, laxogenin. It is a synthetic spirostane-type steroid, which is contained in dietary supplements and advertised as anabolic agent. 

Description

5α-hydroxy Laxogenin is a brassinosteroid analog and a derivative of diosgenin.Topical administration of 5α-hydroxy laxogenin (4, 8, and 12 ppm), in combination with a commercial fertilizer, increases the yield and fresh weight of endives (C. endivia).It also inhibits sodium chloride-induced decreases in the fresh weight of lettuce shoots and roots when applied topically at concentrations of 0.1 and 1 μM, as well as inhibits increases in ethylene emission at a concentration of 1 μM.

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