Ald-Ph-PEG2-NHBoc
Ald-Ph-PEG2-NHBoc Basic information
- Product Name:
- Ald-Ph-PEG2-NHBoc
- Synonyms:
-
- Ald-Ph-PEG2-NHBoc
- DF-PEG2-NH-Boc
- CHO-Ph-CONH-PEG2-NHBoc
- 5,8-Dioxa-2,11-diazadodecanoic acid, 12-(4-formylphenyl)-12-oxo-, 1,1-dimethylethyl ester
- CAS:
- 1807503-90-7
- MF:
- C19H28N2O6
- MW:
- 380.44
- Mol File:
- 1807503-90-7.mol
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Ald-Ph-PEG2-NHBoc Chemical Properties
- Boiling point:
- 581.3±50.0 °C(Predicted)
- Density
- 1.147±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C, stored under nitrogen
- form
- Viscous Liquid
- pka
- 12.22±0.46(Predicted)
- color
- Colorless to light yellow
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Ald-Ph-PEG2-NHBoc Usage And Synthesis
Description
Ald-Ph-PEG2-NH-Boc is a PEG linker containing a benzaldehyde group which is able to undergo reactions with aminooxy moiety The Boc protected amine can be deprotected under acidic for further reaction
Uses
Ald-Ph-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Ald-Ph-PEG2-NHBocSupplier
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