Basic information Safety Supplier Related

BMS-986020

Basic information Safety Supplier Related

BMS-986020 Basic information

Product Name:
BMS-986020
Synonyms:
  • BMS-986020
  • CS-2492
  • (R)-1-(4'-(3-methyl-4-(((1-phenylethoxy)carbonyl)amino)isoxazol-5-yl)-[1,1'-biphenyl]-4-yl)cyclopropane-1-carboxylic acid
  • BMS-986020;BMS 986020;BMS986020
  • 1-{4'-[3-methyl-4-((R)-1-phenyl-ethoxycarbonylamino)-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid
  • AM152
  • Cyclopropanecarboxylic acid, 1-[4'-[3-methyl-4-[[[(1R)-1-phenylethoxy]carbonyl]amino]-5-isoxazolyl][1,1'-biphenyl]-4-yl]-
  • inhibit,idiopathic,AM-152,LPL Receptor,Lysophospholipid Receptor,AM 152,IPF,BMS-986020,fibrosis,pulmonary,BMS 986020,autoradiography,Inhibitor,ARG
CAS:
1257213-50-5
MF:
C29H26N2O5
MW:
482.53
Mol File:
1257213-50-5.mol
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BMS-986020 Chemical Properties

Melting point:
174-180°C
Boiling point:
664.8±55.0 °C(Predicted)
Density 
1.309±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly), Methanol (Slightly, Sonicated)
form 
Solid
pka
4.19±0.20(Predicted)
color 
White to Off-White
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BMS-986020 Usage And Synthesis

Description

BMS 986020 is a potent G protein-coupled lysophosphatidic acid receptor 1 (LPA1) antagonist with an IC50 value less than 300 nM for human LPA1 expressing CHO cells. Formulations containing BMS 986020 are being investigated in clinical trials for efficacy in idiopathic pulmonary fibrosis.

Uses

BMS-?986020 is an LPA-1 antagonist which may be used in the inhibition and treatment of bleomycin-induced pulminary fibrosis.

BMS-986020Supplier

Kaixin Chemical (Hong Kong) Limited Gold
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010-88886666-01 13112345678
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loyson@tcypharm.com
Shanghai Boyle Chemical Co., Ltd.
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sales@boylechem.com
Haoyuan Chemexpress Co., Ltd.
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021-58950125
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info@chemexpress.com
SHANGHAI SINOCHEMTECH CO.,LTD.
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86-21-37788339
Shanghai XingMo Biotechnology Co., Ltd.
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13524779951
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2075692521@qq.com