Basic information Safety Supplier Related

BMS-986020

Basic information Safety Supplier Related

BMS-986020 Basic information

Product Name:
BMS-986020
Synonyms:
  • BMS-986020
  • CS-2492
  • (R)-1-(4'-(3-methyl-4-(((1-phenylethoxy)carbonyl)amino)isoxazol-5-yl)-[1,1'-biphenyl]-4-yl)cyclopropane-1-carboxylic acid
  • BMS-986020;BMS 986020;BMS986020
  • 1-{4'-[3-methyl-4-((R)-1-phenyl-ethoxycarbonylamino)-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid
  • AM152
  • Cyclopropanecarboxylic acid, 1-[4'-[3-methyl-4-[[[(1R)-1-phenylethoxy]carbonyl]amino]-5-isoxazolyl][1,1'-biphenyl]-4-yl]-
  • inhibit,idiopathic,AM-152,LPL Receptor,Lysophospholipid Receptor,AM 152,IPF,BMS-986020,fibrosis,pulmonary,BMS 986020,autoradiography,Inhibitor,ARG
CAS:
1257213-50-5
MF:
C29H26N2O5
MW:
482.53
Mol File:
1257213-50-5.mol
More
Less

BMS-986020 Chemical Properties

Melting point:
174-180°C
Boiling point:
664.8±55.0 °C(Predicted)
Density 
1.309±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly), Methanol (Slightly, Sonicated)
form 
Solid
pka
4.19±0.20(Predicted)
color 
White to Off-White
More
Less

BMS-986020 Usage And Synthesis

Description

BMS 986020 is a potent G protein-coupled lysophosphatidic acid receptor 1 (LPA1) antagonist with an IC50 value less than 300 nM for human LPA1 expressing CHO cells. Formulations containing BMS 986020 are being investigated in clinical trials for efficacy in idiopathic pulmonary fibrosis.

Uses

BMS-?986020 is an LPA-1 antagonist which may be used in the inhibition and treatment of bleomycin-induced pulminary fibrosis.

BMS-986020Supplier

Kaixin Chemical (Hong Kong) Limited Gold
Tel
010-88886666-01 13112345678
Email
loyson@tcypharm.com
Shanghai Boyle Chemical Co., Ltd.
Tel
Email
sales@boylechem.com
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Email
info@chemexpress.com
SHANGHAI SINOCHEMTECH CO.,LTD.
Tel
86-21-37788339
Shanghai XingMo Biotechnology Co., Ltd.
Tel
+86 13524779951; 13524779951
Email
2075692521@qq.com