Basic information Safety Supplier Related

Oxo Enzalutamide

Basic information Safety Supplier Related

Oxo Enzalutamide Basic information

Product Name:
Oxo Enzalutamide
Synonyms:
  • Oxo Enzalutamide
  • 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-2,4-dioxo-1-imidazolidinyl]-2-fluoro-N-methylbenzamide
  • Benzamide, 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-2,4-dioxo-1-imidazolidinyl]-2-fluoro-N-methyl-
  • Enzalutamide Impurity J/ Enzalutamide Oxo Impurity
  • Enzalutamide Impurities750
  • Enzalutamide Impurities5
  • EZ-YHAPI
  • 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide? (Enzalutamide Impurity)
CAS:
1242137-18-3
MF:
C21H16F4N4O3
MW:
448.37
Mol File:
1242137-18-3.mol
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Oxo Enzalutamide Chemical Properties

Density 
1.48±0.1 g/cm3(Predicted)
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
13.99±0.46(Predicted)
color 
White to Off-White
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Oxo Enzalutamide Usage And Synthesis

Uses

Oxo-MDV 3100 (Oxo-enzalutamide) is an impurity of Enzalutamide (M199800), which is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. Enzalutamide has been shown to induce tumor cell apoptosis, and is used for the treatment of castration-resistant prostate cancer.

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