Niazinin Chemical Properties

Boiling point:

527.4±60.0 °C(Predicted)

Density 

1.387±0.06 g/cm3(Predicted)

pka

12.93±0.70(Predicted)

form 

Solid

color 

Off-white to light yellow

Niazinin Usage And Synthesis

Uses

Niazinin is a thiocarbamate glycoside with antileishmanial activities, with an IC50 value of 5.25 μM. Niazinin also shows a binding affinity with the target protein 3CL protease. Niazinin has promising leishmanicidal, anti-inflammatory and anti-pyretic activity[1][2].

IC 50

Leishmania

References

[1] Amandeep Kaur, et al. Antileishmanial compounds from Moringa oleifera Lam. Z Naturforsch C J Biosci. Mar-Apr 2014;69(3-4):110-6. DOI:10.5560/znc.2013-0159
[2] Shiv Rakesh Naik, et al. Structure-based virtual screening, molecular dynamics and binding affinity calculations of some potential phytocompounds against SARS-CoV-2. J Biomol Struct Dyn. 2021 Mar 8;1-18. DOI:10.1080/07391102.2021.1891969

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