ChemicalBook > Product Catalog > Chemical Reagents > Organic reagents > Imide > IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER
IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER
IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER Basic information
- Product Name:
- IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER
- Synonyms:
-
- N-HydroxysucciniMide Iodoacetic Acid Ester
- N-IodoacetoxysucciniMide
- Iodoacetic Acid N-Succinimidyl Ester N-(Iodoacetoxy)succinimide
- 2,5-Pyrrolidinedione, 1-[(iodoacetyl)oxy]-
- N-SucciniMidyl iodoacetate(SIA)
- SIA
- N-HYDROXYSUCCINIMIDYL IODOACETATE
- NHS IODOACETATE
- CAS:
- 39028-27-8
- MF:
- C6H6INO4
- MW:
- 283.02
- Product Categories:
-
- MTS and Sulfhydryl Active Reagents
- Heterobifunctional Crosslinker
- Cross Linking Reagents
- MTS & Sulfhydryl Active Reagents
- Active Esters/AdditivesProtein Modification
- heteroXlink
- Active Esters/AdditivesSynthetic Reagents
- Coupling
- Crosslinking
- Heterobifunctional Cross-Linking Reagents
- Peptide Synthesis
- Mol File:
- 39028-27-8.mol
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IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER Chemical Properties
- Melting point:
- 148°C
- Boiling point:
- 315.6±44.0 °C(Predicted)
- Density
- 2.11±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMF: 50 mg/mL
- form
- powder
- color
- White to Off-White
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MSDS
- Language:English Provider:SigmaAldrich
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IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER Usage And Synthesis
Description
SIA Crosslinker is a non-cleavable, water-soluble crosslinker containig an NHS ester and an iodine group. The NHS ester is reactive toward amines while the iodine reacts with thiol groups.
Chemical Properties
White Solid
Uses
A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 1.5 Angstroms
Uses
forms water soluble carboxylate derivatives
Uses
A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 1.5 Angstroms
Biological Activity
SIA Crosslinker is a non-cleavable ADC linker that can be used to synthesize antibody drug conjugates (ADCs).
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTERSupplier
Wuhan Brin Technology Co., Ltd. Gold
- Tel
- 3456065315 13260619011
- 3456065315@qq.com
Nanjing Habo Medical Technology Co., Ltd. Gold
- Tel
- 025-85760892 13376090521
- sales@habotech.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel
- 021-61259108 18621169109
- market03@meryer.com
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
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IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER(39028-27-8)Related Product Information
- N-succinimidyl-4-((iodoacetyl)amino)benzoate
- N-Succinimidyl 4-(4-maleimidophenyl)butyrate
- TARTRONIC ACID
- 4'-Hydroxyacetophenone
- 2,5-dioxopyrrolidin-1-yl pent-4-ynoate
- Alkyne NHS ester (hexynoic acid NHS ester)
- 2,5-dioxopyrrolidin-1-yl 4-ethynylbenzoate
- 2,5-dioxopyrrolidin-1-yl 3-ethynylbenzoate
- Iodoacetic acid
- DISUCCINIMIDYL SUCCINATE
- 2-Iodoethanol
- DISULFOSUCCINIMIDYL-L-TARTRATE
- IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER