SUC-ALA-ALA-PRO-PHE-PNA Chemical Properties

storage temp. 

-20°C

solubility 

DMF: 25 mg/mL, clear, light yellow

form 

White to off-white solid

BRN 

4289896

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

F 

10

HS Code 

2933998090

MSDS

• Language:English Provider:SigmaAldrich

SUC-ALA-ALA-PRO-PHE-PNA Usage And Synthesis

Description

Suc-AAPF-pNA is a chromogenic substrate that can be cleaved by cathepsin G (K_m = 1.7 mM), subtilisins, chymotrypsin (K_m = 60 μM), chymase (K_m = 4 mM), and cyclophilin, but not neutrophil elastase. Release of p-nitroanilide is monitored at 405-410 nm. This substrate can be used for inhibitor screening and kinetic analysis.

Uses

N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide has been used as a substrate to determine chymotrypsin activity.

Biochem/physiol Actions

N-succinyl-Ala-Ala-Pro-Phe p-nitroanilide is a substrate for subtilisin and proteases.

SUC-ALA-ALA-PRO-PHE-PNA(70967-97-4)Related Product Information

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