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(R)-N-Glycidylphthalimide

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(R)-N-Glycidylphthalimide Basic information

Product Name:
(R)-N-Glycidylphthalimide
Synonyms:
  • (R)-(-)-N-(2,3-Epoxypropyl)phthaliMide, ee: 98%
  • 2-[(2R)-oxiran-2-ylmethyl]-1H-isoindol-1,3(2H)-dione
  • 1H-Isoindole-1,3(2H)-dione,2-[(2R)-2-oxiranylMethyl]-
  • (R)-(-)-N-(2,3-Epoxypropyl)phthaliMide >=99.0% (GC)
  • (R)-2-OXIRANYLMETHYL-ISOINDOLE-1,3-DIONE
  • (R)-(-)-GLYCIDYL PHTHALIMIDE
  • (R)-GLYCIDYL PHTHALIMIDE
  • (R)-(-)-N-(2,3-Epoxypropyl)phthalimide
CAS:
181140-34-1
MF:
C11H9NO3
MW:
203.19
EINECS:
629-091-0
Product Categories:
  • N-Substituted Maleimides, Succinimides & Phthalimides
  • N-Substituted Phthalimides
  • Oxiranes
  • Simple 3-Membered Ring Compounds
Mol File:
181140-34-1.mol
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(R)-N-Glycidylphthalimide Chemical Properties

Melting point:
101 °C
Boiling point:
347.4±15.0 °C(Predicted)
Density 
1.446±0.06 g/cm3 (20 ºC 760 Torr)
refractive index 
-10 ° (C=2.2, CHCl3)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
-2.24±0.20(Predicted)
color 
White
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Safety Information

Hazard Codes 
Xi
Risk Statements 
41
Safety Statements 
26-39
WGK Germany 
2
HS Code 
29251900
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(R)-N-Glycidylphthalimide Usage And Synthesis

Chemical Properties

White solid

Uses

(R)-(-)-N-(2,3-Epoxypropyl)phthalimide may be used in the preparation of the following potential chiral solvating agents:

  • 2-[(2R)-2-hydroxy-3-[[(1R)-2-hydroxy-1-phenyl-ethyl]amino]propyl] isoindoline-1,3-dione
  • 2-[(2R)-2-hydroxy-3-[[(1R,2S)-2-hydroxyindan-1-yl]amino]propyl]isoindoline-1,3-dione
  • 2-[(2R)-2-hydroxy-3-[[(1R)-1-(hydroxymethyl)-propyl]amino]propyl] isoindoline-1,3-dione
  • 2-[(2R)-2-hydroxy-3-[[(1S)-1-phenylethyl]-amino]propyl]isoindoline-1,3-dione
It may also be used in the synthesis of 2-((5R)-2-oxo-5-oxazolidinyl) methyl)-1H-isoindole-1,3 (2H)-dione.

Uses

(R)-N-Glycidylphthalimide is a reagent used for the simultaneous preparation of amino alcohol solvating agents as well as preparation of orally available anticoagulants.

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