tert-Butyl phenyl carbonate Chemical Properties

Boiling point:

83 °C/0.6 mmHg (lit.)

Density 

1.05 g/mL at 20 °C (lit.)

refractive index 

n20/D 1.480

Flash point:

214 °F

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Chloroform (Slightly)

form 

Liquid or Low Melting Solid

color 

Colorless

Water Solubility 

Slightly soluble in water.

BRN 

2361602

NIST Chemistry Reference

Carbonic acid 1,1-dimethylethyl ester(6627-89-0)

Safety Information

Safety Statements 

23-24/25

WGK Germany 

3

F 

21

HS Code 

29209090

MSDS

• Language:English Provider:SigmaAldrich

tert-Butyl phenyl carbonate Usage And Synthesis

Chemical Properties

Clear light yellow liquid

Uses

tert-Butyl phenyl carbonate is used in determination of octanol-water partition coefficients by microemulsion electrokinetic chromatography. It is also used in the synthesis of 2-nitroindoles and as a reagent for mono-Boc protection of α,ω-diamines.

Purification Methods

If IR is free from OH, then purify it by redistillation; otherwise dissolve it in Et2O, wash it with 5% HCl, then H2O, dry it (MgSO4), evaporate and distil it through a Claisen head under vacuum. Care should be taken as distillation of large quantities can lead to decomposition with liberation of CO2 and isobutylene; use the necessary precautions. [Carpino J Am Chem Soc 79 98 1957, Beilstein 6 IV 629.]

tert-Butyl phenyl carbonate(6627-89-0)Related Product Information

• BOC-OIC-OH
• tert-Butylhydrazine hydrochloride
• (4-TERT-BUTOXYCARBOXYPHENYL)BORONIC ACID
• tert-Butyl phenyl carbonate
• 3-(TERT-BUTOXYCARBONYL)PHENYLBORONIC ACID
• T -BUTYL-P-NITROPHENYL CARBONATE
• TERT-BUTYL PENTACHLOROPHENYL CARBONATE
• P-O-T-BOC-BENZYL ALCOHOL
• BPOC REAGENT
• DIBOC-6-TRIMETHYLSTANNYL-L-PHENYLALANINE ETHYL ESTER
• Tert-Butyl 4-Vinylphenyl Carbonate
• TERT-BUTYL-3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL CARBONATE
• CARBONIC ACID TERT-BUTYL 2,4,5-TRICHLOROPHENYL ESTER
• BOC-TYR(BOC)-OH
• P-O-T-BOC-BENZYLMETHANETHIOSULFONATE
• TERT-BUTYL 4-FORMYLPHENYL CARBONATE
• TERT-BUTYL 4-FORMYL-2-METHOXYPHENYL CARB ONATE, 99
• Cholesterylp-tert.butylphenylcarbonate