METHOXYVERAPAMIL HYDROCHLORIDE
METHOXYVERAPAMIL HYDROCHLORIDE Basic information
- Product Name:
- METHOXYVERAPAMIL HYDROCHLORIDE
- Synonyms:
-
- 5-[(3,4-Dimethoxyphenethyl)methylamino]-2-isopropyl-2-(3,4,5-trimethoxyphenyl)valeronitrile
- 5-[[2-(3,4-Dimethoxyphenyl)ethyl](methyl)amino]-2-isopropyl-2-(3,4,5-trimethoxyphenyl)pentanenitrile
- Methoxyverapamil
- C13764
- 5-((3,4-diMethoxyphenethyl)(Methyl)aMino)-2-isopropyl-2-(3,4,5-triMethoxyphenyl)pentanenitrile
- 5-((3,4-diMethoxyphenethyl)(Methyl)aMino)-2-isopropyl-2-(3,4,5-triMethoxyphenyl)pentanenitrile HCl
- CoMpound D 600
- D 600 (vasodilator)
- CAS:
- 16662-47-8
- MF:
- C28H40N2O5
- MW:
- 484.63
- Mol File:
- 16662-47-8.mol
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METHOXYVERAPAMIL HYDROCHLORIDE Chemical Properties
- Boiling point:
- 605.9±55.0 °C(Predicted)
- Density
- 1.068±0.06 g/cm3(Predicted)
- refractive index
- nD25 1.5402
- storage temp.
- Store at -20°C
- solubility
- DMSO: 100 mg/mL (206.34 mM)
- form
- White to off-white solid.
- pka
- 8.96±0.50(Predicted)
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METHOXYVERAPAMIL HYDROCHLORIDE Usage And Synthesis
Uses
(±)-Methoxyverapamil hydrochloride has been used:
- as calcium channel antagonist in Schistosoma mansoni parasite
- as calcium entry blocker in cultured macrophages
- in the inhibition of L-type voltage gated Ca2+-channels
Definition
ChEBI: Gallopamil is a member of benzenes and an organic amino compound.
General Description
Methoxyverapamil is a calmodulin antagonist. It controls flagellar glycoprotein redistribution by modulating calcium signalling. Methoxyverapamil impacts the effect of intracellular calcium levels and affects the sperm capacitation function.
Biochem/physiol Actions
Blocks L-type Ca2+ channels
Side effects
Gallopamil has a distinctly stronger effect than verapamil but a similar activity profile , .
METHOXYVERAPAMIL HYDROCHLORIDESupplier
Chembest Research Laboratories Limited
- Tel
- 021-20908456
- sales@BioChemBest.com
Beijing HuaMeiHuLiBiological Chemical
- Tel
- 010-56205725
- waley188@sohu.com
Acesys Pharmatech
- Tel
- 18860950986
- tangmanman@zenjipharma.com
Sigma-Aldrich
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
Alta Scientific Co., Ltd.
- Tel
- 022-6537-8550 15522853686
- sales@altasci.com.cn
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METHOXYVERAPAMIL HYDROCHLORIDE(16662-47-8)Related Product Information
- (+)-METHOXYVERAPAMIL HYDROCHLORIDE
- Gabapentin
- Flunarizine dihydrochloride
- Isradipine
- Cilnidipine
- Ryanodine
- Nimodipine
- CHARYBDOTOXIN
- Nicardipine hydrochloride
- DOTARIZINE
- (S)-Verapamilamide
- Nifedipine
- OMEGA-AGATOXIN TK
- Vernakalant Impurity 3 ((3S,1'R,2'S)-Isomer)
- N-methylsulfamide
- Vernakalant Impurity 4 ((3S,1'S,2'R)-Isomer)
- KPKUVVDIZJKERG-WGVGGRBOSA-N
- D 517-d7 Hydrochloride (VerapaMil IMpurity)