Basic information Safety Supplier Related

METHOXYVERAPAMIL HYDROCHLORIDE

Basic information Safety Supplier Related

METHOXYVERAPAMIL HYDROCHLORIDE Basic information

Product Name:
METHOXYVERAPAMIL HYDROCHLORIDE
Synonyms:
  • 5-[(3,4-Dimethoxyphenethyl)methylamino]-2-isopropyl-2-(3,4,5-trimethoxyphenyl)valeronitrile
  • 5-[[2-(3,4-Dimethoxyphenyl)ethyl](methyl)amino]-2-isopropyl-2-(3,4,5-trimethoxyphenyl)pentanenitrile
  • Methoxyverapamil
  • C13764
  • 5-((3,4-diMethoxyphenethyl)(Methyl)aMino)-2-isopropyl-2-(3,4,5-triMethoxyphenyl)pentanenitrile
  • 5-((3,4-diMethoxyphenethyl)(Methyl)aMino)-2-isopropyl-2-(3,4,5-triMethoxyphenyl)pentanenitrile HCl
  • CoMpound D 600
  • D 600 (vasodilator)
CAS:
16662-47-8
MF:
C28H40N2O5
MW:
484.63
Mol File:
16662-47-8.mol
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METHOXYVERAPAMIL HYDROCHLORIDE Chemical Properties

Boiling point:
605.9±55.0 °C(Predicted)
Density 
1.068±0.06 g/cm3(Predicted)
refractive index 
nD25 1.5402
storage temp. 
Store at -20°C
solubility 
DMSO: 100 mg/mL (206.34 mM)
form 
White to off-white solid.
pka
8.96±0.50(Predicted)
color 
White to off-white
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Safety Information

WGK Germany 
3
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METHOXYVERAPAMIL HYDROCHLORIDE Usage And Synthesis

Uses

(±)-Methoxyverapamil hydrochloride has been used:

  • as calcium channel antagonist in Schistosoma mansoni parasite
  • as calcium entry blocker in cultured macrophages
  • in the inhibition of L-type voltage gated Ca2+-channels

Definition

ChEBI: Gallopamil is a member of benzenes and an organic amino compound.

General Description

Methoxyverapamil is a calmodulin antagonist. It controls flagellar glycoprotein redistribution by modulating calcium signalling. Methoxyverapamil impacts the effect of intracellular calcium levels and affects the sperm capacitation function.

Biochem/physiol Actions

Blocks L-type Ca2+ channels

Side effects

Gallopamil has a distinctly stronger effect than verapamil but a similar activity profile , .

METHOXYVERAPAMIL HYDROCHLORIDESupplier

Chembest Research Laboratories Limited
Tel
+86-21-20908456
Email
sales@BioChemBest.com
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Email
waley188@sohu.com
Acesys Pharmatech
Tel
18860950986
Email
tangmanman@zenjipharma.com
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Alta Scientific Co., Ltd.
Tel
022-6537-8550 15522853686
Email
sales@altasci.com.cn
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METHOXYVERAPAMIL HYDROCHLORIDE(16662-47-8)Related Product Information