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DL-4-Amino-3-hydroxybutyric acid

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DL-4-Amino-3-hydroxybutyric acid Basic information

Product Name:
DL-4-Amino-3-hydroxybutyric acid
Synonyms:
  • 4-Amino-3-hydroxybutanoate
  • 4-amino-3-hydroxy-butyricaci
  • gamibetal
  • gamma-amino-beta-hydroxybutyricacid
  • Aminohydroxybutyricacid
  • DL(-3-hydroxy-4-amino butyric acid
  • alpha-Hydroxy-gamma-aminobutan
  • DL-4-AMINO-3-HYDROXY BUTYRIC ACID [GABOB]
CAS:
352-21-6
MF:
C4H9NO3
MW:
119.11916
EINECS:
206-518-5
Product Categories:
  • Organic acids
Mol File:
352-21-6.mol
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DL-4-Amino-3-hydroxybutyric acid Chemical Properties

Melting point:
157-161°C
Boiling point:
220.63°C (rough estimate)
Density 
1.3492 (rough estimate)
refractive index 
1.4540 (estimate)
CAS DataBase Reference
352-21-6(CAS DataBase Reference)
EPA Substance Registry System
Butanoic acid, 4-amino-3-hydroxy-(352-21-6)

MSDS

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DL-4-Amino-3-hydroxybutyric acid Usage And Synthesis

Definition

ChEBI: Gamma-amino-beta-hydroxybutyric acid is a gamma-amino acid comprising 4-aminobutyric acid having a 2-hydroxy substituent. It is a gamma-amino acid and a 3-hydroxy monocarboxylic acid. It is functionally related to a butyric acid. It is a conjugate acid of a 4-amino-3-hydroxybutanoate. It is a tautomer of a gamma-amino-beta-hydroxybutyric acid zwitterion.

Purification Methods

Purify GABOB through a Dowex 50Wx8 resin, eluting with 1.3N NH4OH, evaporating and crystallising the residue by dissolving it in H2O and adding EtOH. It is an anticonvulsant. [Renaud & Seebach Synthesis 424 1986, Takano et al. Tetrahedron Lett 29 795 1988, Beilstein 4 IV 3187.]

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