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(S)-(-)-4-Amino-2-hydroxybutyric acid

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(S)-(-)-4-Amino-2-hydroxybutyric acid Basic information

Product Name:
(S)-(-)-4-Amino-2-hydroxybutyric acid
Synonyms:
  • L-(-)-ALPHA-HYDROXY-GAMMA-AMINOBUTYRIC ACID
  • (S)-4-AMINO-2-HYDROXYBUTANOIC ACID
  • (S)-(-)-4-AMINO-2-HYDROXYBUTYRIC ACID
  • (S)-4-AMINO-2-HYDROXYBUTYRIC ACID
  • L-(-)-alpha-hydroxy-γ-amino butyric acid(HABA)
  • (R)-(-)-4-Amino-2-hydroxybutyricacid
  • (S)-(-)-4-AMINO-2-HYDROXYBUTYRIC ACID, 9 6%
  • (S)-(-)-AMINO-2-HYDROXYBUTYRIC ACID
CAS:
40371-51-5
MF:
C4H9NO3
MW:
119.12
Product Categories:
  • Carboxylic Acids
  • Chiral Building Blocks
  • chiral
  • API intermediates
  • Organic Building Blocks
Mol File:
40371-51-5.mol
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(S)-(-)-4-Amino-2-hydroxybutyric acid Chemical Properties

Melting point:
200-203 °C (lit.)
alpha 
-30 º (c=1, water)
Boiling point:
222.38°C (rough estimate)
Density 
1.3126 (rough estimate)
refractive index 
-30 ° (C=1, H2O)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
Methanol (Very Slightly, Heated), Water
form 
Crystalline Powder, Crystals and/or Chunks
pka
3.47±0.10(Predicted)
color 
White to beige
optical activity
[α]23/D 30°, c = 1 in H2O
Water Solubility 
almost transparency
Sensitive 
Hygroscopic
Stability:
Hygroscopic
InChIKey
IVUOMFWNDGNLBJ-VKHMYHEASA-N
CAS DataBase Reference
40371-51-5(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
37/39-26
WGK Germany 
3
HS Code 
29225090

MSDS

  • Language:English Provider:ACROS
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(S)-(-)-4-Amino-2-hydroxybutyric acid Usage And Synthesis

Chemical Properties

white to light yellow crystal powder

Uses

(S)-(-)-4-Amino-2-hydroxybutyric Acid is an analogue of γ-aminobutyric acid (GABA) with potential inhibitory activity on GABA binding and uptake by brain. Injection of (S)-(-)-4-Amino-2-hydroxybutyric Acid showed no significant changes in plasma growth hormone (GH) in healthy patients but increased plasma GH, prolactin, and cortisol levels in cerebrovascular patients.

Uses

(S)-(-)-4-Amino-2-hydroxybutyric acid may be used in the preparation of 6′-amino-1-N-[(S)-4-amino-2-hydroxybutyryl]-6′-deoxylividomycin A.

General Description

(S)-(-)-4-Amino-2-hydroxybutyric acid is an important moiety of butirosin, an aminoglycoside antibiotic.

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