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Ethyl 4-hydroxypyrimidine-5-carboxylate

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Ethyl 4-hydroxypyrimidine-5-carboxylate Basic information

Product Name:
Ethyl 4-hydroxypyrimidine-5-carboxylate
Synonyms:
  • 6-Hydroxypyrimidine-5-carboxylic acid ethyl ester
  • 4-hydroxy-5-pyrimidinecarboxylicaciethylester
  • ETHYL 4-HYDROXYPYRIMIDINE-5-CARBOXYLATE
  • 6-OXO-1,6-DIHYDRO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER
  • 4-HYDROXY-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER
  • 5-Pyrimidinecarboxylic acid, 1,4-dihydro-4-oxo-, ethyl ester
  • Ethyl 6-oxo-1,6-dihydropyrimidine-5-carboxylate LR
  • Ethyl 1,4-dihydro-4-oxo-5-pyrimidinecarboxylate
CAS:
4786-52-1
MF:
C7H8N2O3
MW:
168.15
Product Categories:
  • pharmacetical
  • Heterocycle-Pyrimidine series
  • CMLLYL
Mol File:
4786-52-1.mol
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Ethyl 4-hydroxypyrimidine-5-carboxylate Chemical Properties

Melting point:
185-186 °C
Density 
1.33±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
pka
7.70±0.40(Predicted)
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Safety Information

HazardClass 
IRRITANT
HS Code 
2933599590
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Ethyl 4-hydroxypyrimidine-5-carboxylate Usage And Synthesis

Uses

7-Chloroisoquinolin-1(2H)-one acts as a reagent for the preparation, SAR of methoxyisoquinoline derivative and discovery of asunaprevir (BMS-650032), an orally efficacious NS3 protease inhibitor for the treatment of hepatitis C virus infection. Synthesis and pharmacological evaluation of a series of 1,2-dihydro-1-[(5-methyl-1-imidazol-4-yl)methyl]-2-oxopyridine 5-HT3 antagonists.

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