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Tenatoprazole

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Tenatoprazole Basic information

Product Name:
Tenatoprazole
Synonyms:
  • 5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)
  • sulfinyl)
  • TENATOPRAZOLE MONOSODIUM
  • Tenatoprazole
  • TENATOPRAZOLE/TU-199
  • 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-imidazo[4,5-β]pyridine
  • 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl] -1H-imidazo[4,5-β]pyridine
  • 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-imidazo[4,5-b]pyridine
CAS:
113712-98-4
MF:
C16H18N4O3S
MW:
346.4
EINECS:
601-277-6
Product Categories:
  • API's
  • Heterocycles
  • Heterocyclic Compounds
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
  • Inhibitors
Mol File:
113712-98-4.mol
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Tenatoprazole Chemical Properties

Melting point:
178-180°C
Boiling point:
570.4±60.0 °C(Predicted)
Density 
1.43±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
DMSO (Slightly, Heated), Methanol (Slightly, Heated)
form 
Solid
pka
4.61±0.40(Predicted)
color 
Off-White to Light Pink
Stability:
Hygroscopic, Temperature Sensitive
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26-36/37
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Tenatoprazole Usage And Synthesis

Description

Tenatoprazole is a proton pump inhibitor, blocking hog gastric H+/K+-ATPase activity with an IC50 value of 6.2 μM. It is orally bioavailable, blocking induced gastric acid secretion and ulcer formation in rats and humans. Tenatoprazole has a prolonged plasma half-life resulting in persistent effectiveness after withdrawal.

Chemical Properties

White Crystalline Powder

Uses

A proton pump inhibitor for reduction and/or prevention of gastrointestinal disorders.

Definition

ChEBI: 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinyl]-1H-imidazo[4,5-b]pyridine is an imidazopyridine.

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