ACETYL COENZYME A TRILITHIUM SALT Chemical Properties

storage temp. 

−20°C

solubility 

Soluble in water (10 mg/ml)

form 

solid

color 

White

Stability:

Stable for 2 years as supplied. Solutions in water may be stored at -20°C for up to 2 weeks.

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37

WGK Germany 

3

F 

3-10-21

HS Code 

2934999090

MSDS

• Language:English Provider:SigmaAldrich

ACETYL COENZYME A TRILITHIUM SALT Usage And Synthesis

Description

Acetyl-CoA (75520-41-1) is an essential cofactor for cellular metabolism, being an ‘activated acetate’ that shuttles its moieties back and forth during anabolic, catabolic, and metabolic processes involving fundamental molecules: fatty acids, amino acids, glucose, and ATP.1 In the laboratory, it can be used as a substrate in chloramphenicol acetyltransferase (CAT) transcription reporter assays2 or in histone acetyltransferase (HAT) assays in epigenetics research3.

Chemical Properties

White amorphous powder

Uses

Acetyl Coenzyme?A Lithium Salt is an important molecule in enzymatic acetyl transfer reactions. It is the source of the phosphopantetheine group that is added as a prosthetic group to acyl carrier proteins and formyltetrahydrofolate dehydrogenase.

References

Wolfe (2005), The acetate switch; Mol. Biol. Rev. 69 12 Gorman et al. (1982), Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells; Mol. Cell Biol. 2 1044 Kim et al. (2000), A continuous, nonradioactive assay for histone acetyltransferases; Anal. Biochem. 280 308

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