Basic information Safety Supplier Related

METHYLMALONYL COENZYME A LITHIUM

Basic information Safety Supplier Related

METHYLMALONYL COENZYME A LITHIUM Basic information

Product Name:
METHYLMALONYL COENZYME A LITHIUM
Synonyms:
  • METHYLMALONYL COENZYME A LITHIUM
  • METHYLMALONYL COENZYME A TETRALITHIUM &
  • methylmalonyl coenzyme a tetralithium salt hydrate
  • α-methylmalonyl coenzyme a tetralithium salt
  • 3-[2-[3-[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]aminopropanoylamino]ethylsulfanyl]-2-methyl-3-oxo-propanoic acid
  • Methylmalonyl-CoA
  • coenzyme A methylmalonyl derivative, tetralithium hydrate
  • coenzyme A methylmalonyl derivative, lithium salt
CAS:
104809-02-1
MF:
C25H41LiN7O19P3S
MW:
875.55
Mol File:
104809-02-1.mol
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METHYLMALONYL COENZYME A LITHIUM Chemical Properties

storage temp. 
-20°C
solubility 
H2O: 50 mg/mL, clear, colorless
form 
Solid
color 
Off-white to light yellow
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-26-36
WGK Germany 
3
10-21
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METHYLMALONYL COENZYME A LITHIUM Usage And Synthesis

Uses

Methylmalonyl coenzyme A (CoA) has been used in the preparation of the calibration curve in ultra-performance liquid chromatography-mass spectrometry (UPLC-MS/MS). It has also been used in the measurement of methylmalonyl-CoA mutase and methylmalonyl-CoA epimerase activity.

Biochem/physiol Actions

Methylmalonyl coenzyme A (CoA) is a catabolite of odd-chain fatty acids, cholesterol and few amino acids like valine, isoleucine, methionine, threonine. It is produced by the activity of the enzyme propionyl-CoA carboxylase(PCC). Methylmalonyl coenzyme A (CoA) is converted to succinyl-CoA by the methylmalonyl-CoA mutase (MCM) and vitamin B12 as the cofactor. Either a low MCM activity or an altered metabolism of vitamin B12 causes the inherited metabolic disease methylmalonic acidemia (MMA).

METHYLMALONYL COENZYME A LITHIUMSupplier

Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
JinJin Le Chemical Co., Ltd
Tel
10106090
Email
jjlchem2@163.com
Energy Chemical
Tel
021-58432009 400-005-6266
Email
marketing1@energy-chemical.com
Shanghai Maclean Biochemical Technology Co., LTD
Tel
021-50706066 15221275939
Email
shenlinxing@macklin.cn
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
18621169109
Email
market03@meryer.com