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trans-1-Cinnamylpiperazine

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trans-1-Cinnamylpiperazine Basic information

Product Name:
trans-1-Cinnamylpiperazine
Synonyms:
  • N-CINNAMYLPIPERAZINE
  • TRANS-1-CINNAMYLPIPERAZINE
  • TIMTEC-BB SBB000411
  • LABOTEST-BB LT00233225
  • 1-TRANS-CINNAMYL PIPERAZINE
  • 1-(3-PHENYL-ALLYL)-PIPERAZINE
  • 1-(CINNAMYL)PIPERAZINE
  • 1-((E)-3-PHENYLALLYL)PIPERAZINE
CAS:
87179-40-6
MF:
C13H18N2
MW:
202.3
EINECS:
673-639-1
Product Categories:
  • Heterocyclic Building Blocks
  • Piperazines
  • Piperaizine
  • Building Blocks
Mol File:
87179-40-6.mol
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trans-1-Cinnamylpiperazine Chemical Properties

Melting point:
39-44 °C(lit.)
Boiling point:
129 °C1 mm Hg(lit.)
Density 
0.989 g/mL at 25 °C(lit.)
refractive index 
1.574-1.576
Flash point:
>230 °F
storage temp. 
Refrigerator, under inert atmosphere
solubility 
Chloroform (Sparingly), Methanol (Slightly)
form 
Solid
pka
9.17±0.10(Predicted)
color 
Pale Yellow
BRN 
608984
InChI
InChI=1S/C13H18N2/c1-2-5-13(6-3-1)7-4-10-15-11-8-14-9-12-15/h1-7,14H,8-12H2/b7-4+
InChIKey
WGEIOMTZIIOUMA-QPJJXVBHSA-N
SMILES
N1(C/C=C/C2=CC=CC=C2)CCNCC1
CAS DataBase Reference
87179-40-6(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
HS Code 
29335995

MSDS

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trans-1-Cinnamylpiperazine Usage And Synthesis

Description

trans-1-Cinnamylpiperazine is a piperazine derivative. It was used as a test compound to investigate the in vitro efficacy as an antiprotozoal against Philasterides dicentrarchi. It may be used to synthesize Incentrom A derivatives.

Chemical Properties

clear colorless to yellow liquid

Uses

trans-1-Cinnamylpiperazine is used in the synthesis of bile acid piperazinyl derivatives which display pro-apoptotic properties on carcinoma human cell lines.

Uses

trans-1-Cinnamylpiperazine was used as a test compound to investigate the in vitro efficacy as an antiprotozoal against Philasterides dicentrarchi. It may be used to synthesize Incentrom A derivatives.

General Description

trans-1-Cinnamylpiperazine is a piperazine derivative.

General Description

trans-1-Cinnamylpiperazine is an important organic synthetic reagent for the preparation of opioid tripeptides hybridised with trans-1-Cinnamylpiperazine, which exhibits low haematotoxicity and good cancer cell growth as an inhibitor of pancreatic cancer cell proliferation in two- and three-dimensional in vitro models Inhibition. It was also used in the preparation of the anticonvulsant active substance cinnamylpiperazine derivatives.

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