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Boc-D-Glutamine

Basic information Safety Supplier Related

Boc-D-Glutamine Basic information

Product Name:
Boc-D-Glutamine
Synonyms:
  • Nalpha-BOC-D-Glutamine,98%
  • (R)-5-amino-2-(tert-butoxycarbonylamino)-5-oxopentanoic acid
  • N-α-Boc-D-glutamine
  • Boc-D-Gln-OH (Boc-D-GlutaMine)
  • Boc-D-Gln-OH >=98.0%
  • BOC-D-GLUTAMINE extrapure
  • (S)-3-(Boc-amino)pentanoic acid 5-amide, Nβ-Boc-L-β-glutamine, Nβ-Boc-L-β-homoasparagine
  • N(^a)-Boc-D-glutamine, 98+%
CAS:
61348-28-5
MF:
C10H18N2O5
MW:
246.26
EINECS:
230-006-0
Product Categories:
  • Boc-Amino Acids and Derivative
  • Amino Acids
Mol File:
61348-28-5.mol
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Boc-D-Glutamine Chemical Properties

Melting point:
117-119°C
Boiling point:
389.26°C (rough estimate)
Density 
1.2430 (rough estimate)
refractive index 
1.4550 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble, 1mmol in 2mL DMF. Soluble in chloroform and methanol.
form 
Solid
pka
3.84±0.10(Predicted)
color 
White to Off-White
BRN 
1981311
CAS DataBase Reference
61348-28-5(CAS DataBase Reference)
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
HS Code 
2924 19 00
HazardClass 
IRRITANT

MSDS

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Boc-D-Glutamine Usage And Synthesis

Chemical Properties

White solid

Uses

N2-Boc-D-glutamine is an N-Boc-protected form of D-Glutamine. D-Glutamine is an unnatural isomer of L-Glutamine that is present in human plasma an is a source of liberated ammonia. D-Glutamine can be synthesized by enzymatic means or can be found in cheeses, wine and vinegars as well.

Biosynthesis

Glutamine is mainly synthesized by the enzyme glutamine synthetase (GS) and hydrolyzed by the enzyme glutaminase (GLS). GS catalyzes glutamine biosynthesis using glutamate and ammonia (NH3) as a source. In this reaction, one ATP is consumed. Glutamate can be donated by many amino acids obtained exogenously (i.e., diet) and/or from endogenous amino acids’ catabolism. On the other hand, GLS is responsible for glutamine hydrolysis to glutamate and ammonium ion (NH4). Almost all cells in the body express GS and GLS, and their predominant expression and activity will dictate if the tissue is more likely to produce or consume glutamine in health and disease[1].

References

[1] Vinicius Cruzat. “Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation.” Nutrients 10 11 (2018).

Boc-D-Glutamine Preparation Products And Raw materials

Preparation Products

Boc-D-GlutamineSupplier

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