D-Glutamine Chemical Properties

Melting point:

184-185 °C

alpha 

-32 º (589nm, c=10, N HCl)

Boiling point:

265.74°C (rough estimate)

Density 

1.3394 (rough estimate)

refractive index 

-33 ° (C=5, 5mol/L HCl)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

Water (Slightly, Sonicated)

pka

2.27±0.10(Predicted)

form 

Powder

color 

White

Water Solubility 

42.53g/L(temperature not stated)

BRN 

1723796

InChIKey

ZDXPYRJPNDTMRX-GSVOUGTGSA-N

LogP

-1.576 (est)

CAS DataBase Reference

5959-95-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

36/37/39-26-27-24/25

WGK Germany 

3

HS Code 

29241900

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

D-Glutamine Usage And Synthesis

Chemical Properties

white crystalline powder

Uses

D-Glutamine is an unnatural isomer of L-Glutamine (G597000) that is present in human plasma an is a source of liberated ammonia. D-Glutamine can be synthesized by enzymatic means or can be found in cheeses, wine and vinegars as well. It is often used to determine the activity of Glutamine synthetase, an enzyme that is commonly found in the mammalian liver and brain that controls the use of nitrogen in cells.

Uses

D-Glutamine has been used to study its role in conferring protection against acetaldehyde-induced disruption of barrier function in Caco-2 cell monolayer.

Definition

ChEBI: The D-enantiomer of glutamine.

General Description

Glutamine is a non-essential and the most abundant free amino acid present in the human body. It is an important component of proteins and is one of the 20 proteinogenic amino acids. It forms 5-6% of bound amino acids.

Biochem/physiol Actions

Glutamine forms the central metabolite in amino acid transamination via a-ketoglutarate and glutamic acid. This amino acid is metabolized by different enzymes, such as glutaminase, present in liver, and glutamine synthetase, present in skeletal muscle. It is produced in the cytoplasm from other amino acids, predominantly from branched-chain amino acids and glutamate. It plays an essential role in ammonia metabolism and detoxification. Its skeletal muscle levels are significantly reduced post trauma, operation and inflammatory states. It servers as a prognostic marker in fatal sepsis during which its skeletal muscle levels are decreased by 90%.

D-Glutamine(5959-95-5)Related Product Information

• Folic acid
• L-Glutamic acid
• Rink Amide Linker
• GLUTAMINE, L-,GLUTAMINE
• Fomesafen
• Polyamide
• Ethyl 2-(Chlorosulfonyl)acetate
• Citric acid
• Glutamic acid
• Ascoric Acid
• MICROCYSTIN YR
• Transglutaminase
• Boc-D-Glutamine
• FMOC-N-DELTA-TRITYL-D-GLUTAMINE
• 9-FLUORENYLMETHOXYCARBONYL-D-GLUTAMINE
• BOC-GLN-ONP
• Z-D-GLN-OH
• L-Alanyl-L-Glutamine