MICROCYSTIN YR Chemical Properties

Density 

1.33±0.1 g/cm3(Predicted)

Flash point:

11 °C

storage temp. 

−20°C

solubility 

methanol: 2  mg/mL (further dilute to 10% (v/v) methanol)

pka

3.02±0.70(Predicted)

form 

white powder

EPA Substance Registry System

Cyclo[2,3-didehydro-N-methylalanyl-D-alanyl-L-tyrosyl-(3S)-3-methyl-D-.beta.-aspartyl-L-arginyl-(2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoyl-D-.gamma.-glutamyl] (101064-48-6)

Safety Information

Hazard Codes 

T+,T,F

Risk Statements 

26/27/28-36/37/38-43-39/23/24/25-23/24/25-11

Safety Statements 

26-36/37/39-45-36/37-16-7

RIDADR 

UN 2811 6.1/PG 1

WGK Germany 

3

RTECS 

000000030272

MSDS

• Language:English Provider:SigmaAldrich

MICROCYSTIN YR Usage And Synthesis

Uses

Microcystin YR from Microcystis aeruginosa has been used to assess cytotoxicity in neutrophils using DNA fragmentation and cell viability assays and as a reference standard in the quantification of microcystin from water samples.

General Description

Microcystin is a potent cyanotoxin produced by the bloom of Microcystis aeruginosa. It is harmful to aquatic animals. It is a heptapeptide and exists as multiple variant forms. pCO₂ and nitrogen levels modulate the toxic variants levels. It elicits damage to the liver and other organs.

Biochem/physiol Actions

Microcystin YR inhibits protein phosphatase type 2A and protein phosphatase type 1. Toxicity to undifferentiated cells was seen by inhibition of neutral red uptake, >80% at 100 μM, after 48 h.

MICROCYSTIN YR(101064-48-6)Related Product Information

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