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BOC-Glycine

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BOC-Glycine Basic information

Product Name:
BOC-Glycine
Synonyms:
  • BOC-Glycine, 99+%
  • Boc-glycin
  • N-tert-Boc-glycine-OH
  • BOC-GLYCINE(N-TERT-BUTOXYCARBONYLGLYCINE)
  • n-[(1,1-dimethylethoxy)carbonyl]-glycin
  • glycine(sterile)
  • N-ALPHA-T-BUTYLOXYCARBONYL-GLYCINE
  • BOC-L-GLY-OH
CAS:
4530-20-5
MF:
C7H13NO4
MW:
175.18
EINECS:
224-864-5
Product Categories:
  • Intermediates & Fine Chemicals
  • Glycine [Gly, G]
  • Amino Acids
  • Boc-Amino Acids and Derivative
  • Amino Acids 13C, 2H, 15N
  • Absolute Configuration Determination (Exciton Chirality CD Method)
  • Amino Acids (N-Protected)
  • Analytical Chemistry
  • Biochemistry
  • Boc-Amino Acids
  • Enantiomer Excess & Absolute Configuration Determination
  • Exciton Chirality CD Methodfor (for Monofunctional Compounds)
  • Boc-Amino acid series
  • Amino Acids & Derivatives
  • Protected Amino Acids
  • AMINOACIDS DERIVATIVES
  • Amino Acid Derivatives
  • PROTECTED AMINO ACID & PEPTIDES
  • Pharmaceuticals
Mol File:
4530-20-5.mol
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BOC-Glycine Chemical Properties

Melting point:
86-89 °C(lit.)
Boiling point:
306.47°C (rough estimate)
Density 
1.2843 (rough estimate)
refractive index 
1.4353 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Powder
pka
4.00±0.10(Predicted)
color 
White to off-white
Water Solubility 
soluble
BRN 
1101514
InChI
InChI=1S/C7H13NO4/c1-7(2,3)12-6(11)8-4-5(9)10/h4H2,1-3H3,(H,8,11)(H,9,10)
InChIKey
VRPJIFMKZZEXLR-UHFFFAOYSA-N
SMILES
C(O)(=O)CNC(OC(C)(C)C)=O
CAS DataBase Reference
4530-20-5(CAS DataBase Reference)
EPA Substance Registry System
Glycine, N-[(1,1-dimethylethoxy)carbonyl]- (4530-20-5)
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Safety Information

Hazard Codes 
Xn,Xi
Risk Statements 
22-41-36/37/38-20/21/22
Safety Statements 
26-36/37/39-39-36
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
TSCA 
Yes
HS Code 
29241990

MSDS

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BOC-Glycine Usage And Synthesis

Chemical Properties

White To Off-White Powder

Uses

Boc-Gly-OH can be used:

  • For the esterification reaction to synthesize N-Boc amino acid esters for peptide chemistry.
  • For the synthesis of tripeptide H-Gly-Pro-Glu-OH, analogs of neuroprotective drugs.
  • As a promoter for the allylation of hydrazones and isatin.

Uses

BOC-Glycine is used in the composition of drugs containing Ketoprofen, and Sodium hyaluronate as antiinflammatory agents.

Synthesis Reference(s)

Tetrahedron Letters, 16, p. 4393, 1975 DOI: 10.1016/S0040-4039(00)91133-X

BOC-Glycine Preparation Products And Raw materials

Raw materials

BOC-GlycineSupplier

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