PALMITOYL GLYCINE Chemical Properties

Melting point:

121 °C(Solv: acetone (67-64-1))

Boiling point:

491.8±28.0 °C(Predicted)

Density 

0.960±0.06 g/cm3(Predicted)

vapor pressure 

0.001Pa at 85℃

storage temp. 

Sealed in dry,2-8°C

solubility 

DMSO: >10mg/mL

pka

3.59±0.10(Predicted)

form 

solid

color 

white to off-white

InChI

InChI=1S/C18H35NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17(20)19-16-18(21)22/h2-16H2,1H3,(H,19,20)(H,21,22)

InChIKey

KVTFEOAKFFQCCX-UHFFFAOYSA-N

SMILES

C(O)(=O)CNC(=O)CCCCCCCCCCCCCCC

LogP

5.85 at 25℃

Safety Information

WGK Germany 

2

PALMITOYL GLYCINE Usage And Synthesis

Chemical Properties

White to off-white powder

Uses

N-palmitoylglycine has been used as an intact polar lipid (IPL) standard for determination of δ 15N values of nitrogen containing headgroups of IPLs using gas chromatography/combustion/isotope-ratio mass spectrometry.

Definition

ChEBI: N-hexadecanoylglycine is an N-acylglycine in which the acyl group is specified as hexadecanoyl (palmitoyl). It has a role as a marine metabolite and a human metabolite. It is a fatty amide and a N-acylglycine 16:0. It is functionally related to a hexadecanoic acid. It is a conjugate acid of a N-hexadecanoylglycinate.

Biological Activity

PalGly is an endogenous signaling lipid th at modulates calcium influx and nitric oxide production. PalGly inhibits heat-evoked firing of wide dynamic range (WDR) neurons, activates calcium influx in DRG cells and stimulates NO production. Preliminary studies suggest its signaling mechanism involves GPCR-mediated cation channel activation and a Gαi/o-coupled signaling pathway, which is being further investigated.

PALMITOYL GLYCINE(2441-41-0)Related Product Information

• Carnauba wax
• Palmitoyl chloride
• PALMITOLEIC ACID METHYL ESTER
• PALMITOLEIC ACID
• Methyl palmitate
• PalMitoyl Tripeptide-1
• Palmitic acid
• Palmitic acid ethyl ester
• dihydrogen bis[N-palmitoyl-L-glutamato(2-)-N,O1]magnesate(2-)
• PALMITOYL GLUTAMIC ACID
• N2-(1-Oxohexadecyl)-L-lysyl-L-valyl-(2S)-2,4-diaminobutanoyl-L-threonine bis(trifluoroacetate) (salt)
• 1-(1-Oxohexadecyl)-L-proline
• Sodium 1-palmitoyl-L-prolinate
• Isopropyl palmitate
• Palm fatty acid
• PALMITIC ACID VINYL ESTER
• 4-NITROPHENYL PALMITATE
• MONOPALMITIN