Palmitic acid ethyl ester Chemical Properties

Melting point:

24-26 °C (lit.)

Boiling point:

192-193 °C/10 mmHg (lit.)

Density 

0.857 g/mL at 25 °C (lit.)

vapor pressure 

0.01Pa at 25℃

refractive index 

n20/D 1.440(lit.)

FEMA 

2451 | ETHYL PALMITATE

Flash point:

>230 °F

storage temp. 

2-8°C

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly)

Specific Gravity

0.857

color 

Colourless to Off-White

Odor

at 100.00 %. mild waxy fruity creamy milky balsamic greasy oily

Odor Type

waxy

Water Solubility 

IMMISCIBLE

JECFA Number

39

BRN 

1782663

Dielectric constant

2.7（103℃）

LogP

7.74

CAS DataBase Reference

628-97-7(CAS DataBase Reference)

NIST Chemistry Reference

Hexadecanoic acid, ethyl ester(628-97-7)

EPA Substance Registry System

Hexadecanoic acid, ethyl ester (628-97-7)

Safety Information

Hazard Codes 

Xi

Safety Statements 

23-24/25

WGK Germany 

3

Hazard Note 

Irritant

TSCA 

Yes

HS Code 

29157020

MSDS

• Language:English Provider:Palmitic acid ethyl ester
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Palmitic acid ethyl ester Usage And Synthesis

Description

Palmitic acid ethyl ester, also known as ethyl palmitate, it the ethyl ester form of palmitic acid. It can be used as a hair- and skin-conditioning agent. It has been shown that the combination between palmitic acid ethyl ester and cobra venom factor can enhance the survival of heterologous erythrocyte. Recent study has also demonstrated the potential anti-inflammatory activity of palmitic acid ethyl ester in several animal models.

Chemical Properties

Ethyl palmitate has a mild, waxy sweet odor. It is nearly tasteless and has a creamy mouthfeel.

Chemical Properties

clear colorless oily liquid after melting

Occurrence

Reported found in mutton, rye bread, rice, bourbon, vanilla, red sage, lemon balm, bilberry, Parmesan cheese, maple syrup, Jamaican rum, whiskey, grape wine, cognac, cocoa, green tea, mango, corn oil and mastic gum leaf oil.

Uses

A fatty acid found in Amaranth oil; it shows inhibitory activity.

Uses

Ethyl palmitate acts as a lubricant on the skin?s surfaces in order to get a soft and smooth appearance. It increases cytosolic Ca2+ concentration leading to pancreatic acinar cell injury due to excessive consumption of ethanol.

Definition

ChEBI: A long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of palmitic acid with the hydroxy group of ethanol.

Aroma threshold values

Detection: 2 ppm

Taste threshold values

Taste characteristics at 30 ppm: waxy, fruity, creamy and fermented with a vanilla, balsamic nuance.

Synthesis Reference(s)

Tetrahedron, 48, p. 8775, 1992 DOI: 10.1016/S0040-4020(01)89450-3

General Description

Ethyl palmitate is a one of the major volatile compounds found in cooked rice and Luzhou-flavor raw liquor. It occurs naturally in licorice root and chamomile.

Synthesis

Synthesized by immobilized lipase-catalyzed alcoholysis and esterification in organic solvents.

References

Beste, Russell D, and R. D. Hamlin. "Skin permeation enhancer compositions comprising a monoglyceride and ethyl palmitate." US, US6267984. 2001.
Castro, O, et al. "Mechanism of ethyl palmitate and cobra venom factor enhancement of heterologous erythrocyte survival. " Proceedings of the Society for Experimental Biology & Medicine Society for Experimental Biology & Medicine 147.1(1974):106.
Saeed, N. M., et al. "Anti-inflammatory activity of methyl palmitate and ethyl palmitate in different experimental rat models. " Toxicology & Applied Pharmacology 264.1(2012):84-93.

Palmitic acid ethyl ester(628-97-7)Related Product Information

• Isopropyl palmitate
• Palmitic acid
• Methyl palmitate
• pendecamaine
• Isooctyl palmitate
• Palmitoyl chloride
• Ethylhexyl Palmitate
• PALMITIC ACID VINYL ESTER
• CETYL PALMITATE
• PALMITELAIDIC ACID
• PALMITOLEIC ACID METHYL ESTER
• PALMITOLEIC ACID
• PalMitoyl Tripeptide-1
• PALMITOYL GLYCINE
• PALMITIC ACID ISOBUTYL ESTER
• ISOHEXYL PALMITATE
• isodecyl palmitate
• Carnauba wax