CETYL PALMITATE Chemical Properties

Melting point:

55-56 °C(lit.)

Boiling point:

360 °C

Density 

d20 0.989

refractive index 

1.4429 (589.3 nm 60℃)

storage temp. 

2-8°C

solubility 

Soluble in hot acetone.

form 

Crystalline Powder

color 

White to almost white

biological source

synthetic (organic)

Merck 

14,2031

Dielectric constant

2.2（Ambient）

InChI

InChI=1S/C32H64O2/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-34-32(33)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h3-31H2,1-2H3

InChIKey

PXDJXZJSCPSGGI-UHFFFAOYSA-N

SMILES

C(OCCCCCCCCCCCCCCCC)(=O)CCCCCCCCCCCCCCC

LogP

15.051 (est)

CAS DataBase Reference

540-10-3(CAS DataBase Reference)

EPA Substance Registry System

Hexadecyl palmitate (540-10-3)

Safety Information

Safety Statements 

24/25

WGK Germany 

-

RTECS 

RT4750000

TSCA 

Yes

HS Code 

29171900

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

CETYL PALMITATE Usage And Synthesis

Chemical Properties

white to almost white crystalline powder

Uses

Palmityl Palmitate is a wax ester of palmitic acid used in cosmetic and personal care products.

Uses

The chemical structure of cetyl palmitate (synthetic spermaceti) is the same as whale spermaceti. It may be used to thicken, produce viscose emulsions, give stability, and add texture to emulsions. It is similar to cetearyl palmitate.

Uses

It is used as emollients, masking agents and skin conditioning and a glosser and thickener for creams. It improves emulsion texture and stability and gives structure to cosmetic sticks. Used in skin and hair applications.

Definition

ChEBI: A palmitate ester resulting from the formal condensation of palmitic acid with palmityl alcohol. It is used as a thickener and emollient in cosmetics.

General Description

Cetyl Palmitate is an ester of palmitic acid, obtained via the reaction of cetyl alcohol and palmitic acid. It is an ingredient of many cosmetic preparations.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Flammability and Explosibility

Not classified

Synthesis

GENERAL METHOD: 1.0 g (7.69 mmol) of 1-hexadecanol was added to a 50 mL round-bottomed flask, followed by 0.523 g (0.66 eq.) of NaBr and 0.383 g (0.33 eq.) of NaBrO3, and 10 mL of H2O [this aqueous solution has a molar ratio of bromide to bromate of 2:1]. The reaction mixture was stirred vigorously to ensure complete dissolution of the contents. An aqueous solution of H2SO4 (0.5 equiv, prepared from 0.21 mL of 98% H2SO4 with 1 mL of water) was slowly added to the above reaction mixture at room temperature with continuous stirring for 2.5 hours. The reaction mixture was continued to be stirred for up to 24 hours. Upon completion of the reaction, the product was extracted with CH2Cl2 (3 x 15 mL) and the organic layer was dried with Na2SO4, followed by removal of the solvent to afford hexadecanoic acid hexadecyl ester in 98% yield (0.953 g) as a colorless liquid. The structure of the product was confirmed by GC-MS and NMR.

References

[1] Synthetic Communications, 2018, vol. 48, # 13, p. 1663 - 1670

CETYL PALMITATE(540-10-3)Related Product Information

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• Palmityl Palmitate