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2-Amino-4-methyl-5-bromopyrimidine

Product Name
2-Amino-4-methyl-5-bromopyrimidine
CAS No.
17321-93-6
Chemical Name
2-Amino-4-methyl-5-bromopyrimidine
Synonyms
100704;5-Bromo-4-methyl-2-pyrimidinamine;2-PyriMidinaMine,5-broMo-4-Methyl-;2-Amino-5-bromo-4-methylpyrimidine;2-amino-4-methyl-5-bromopyrimidine;5-Bromo-4-methyl-2-aminopyrimidine;5-Bromo-2-amino-4-methylpyrimidine;5-bromo-4-methylpyrimidine-2-ylamine;5-BROMO-4-METHYL-PYRIMIDIN-2-YLAMINE;2-AMino-5-broMo-4-MethylpyriMidine 97%
CBNumber
CB01010770
Molecular Formula
C5H6BrN3
Formula Weight
188.03
MOL File
17321-93-6.mol
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2-Amino-4-methyl-5-bromopyrimidine Property

Melting point:
192-194℃
Boiling point:
345.4±34.0 °C(Predicted)
Density 
1.699±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
solid
pka
2.47±0.10(Predicted)
Appearance
White to light yellow Solid
InChI
InChI=1S/C5H6BrN3/c1-3-4(6)2-8-5(7)9-3/h2H,1H3,(H2,7,8,9)
InChIKey
LPQVTZJEIXYDQA-UHFFFAOYSA-N
SMILES
C1(N)=NC=C(Br)C(C)=N1
CAS DataBase Reference
17321-93-6
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Safety

Hazard Codes 
Xn
Risk Statements 
22-37/38-41
Safety Statements 
26-39
WGK Germany 
3
TSCA 
N
HS Code 
29335990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
715085
Product name
2-Amino-5-bromo-4-methylpyrimidine
Purity
97%
Packaging
1g
Price
$68.8
Updated
2023/06/20
TRC
Product number
A602188
Product name
2-Amino-5-bromo-4-methylpyrimidine
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
A602188
Product name
2-Amino-5-bromo-4-methylpyrimidine
Packaging
500mg
Price
$75
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-9-CW
Product name
2-Amino-4-methyl-5-bromopyrimidine
Purity
95%
Packaging
1g
Price
$16
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA12130
Product name
2-Amino-4-methyl-5-bromopyrimidine
Packaging
2g
Price
$189
Updated
2021/12/16
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2-Amino-4-methyl-5-bromopyrimidine Chemical Properties,Usage,Production

Synthesis

108-52-1

17321-93-6

General procedure for the synthesis of 2-amino-4-methyl-5-bromopyrimidine from 2-amino-4-methylpyrimidine: To a solution of 4-methylpyrimidin-2-ylamine (10.9 g, 100 mmol) in chloroform (400 mL) was added N-bromosuccinimide (17.8 g, 100 mmol). The reaction mixture was stirred under light-avoiding conditions for 15 hours. Upon completion of the reaction, the mixture was transferred to dichloromethane (140 mL) and washed sequentially with 1N sodium hydroxide solution (3 x 200 mL) and saturated sodium chloride solution (100 mL). The organic phase was dried with anhydrous sodium sulfate, filtered and concentrated to give 5-bromo-4-methylpyrimidin-2-ylamine (18.8 g, 99% yield). The product was detected by LCMS (m/z): 188.0/190.0 (MH+). 1H NMR (CDCl3) data: δ 8.22 (s, 1H), 5.02 (bs, 2H), 2.44 (s, 3H).

References

[1] Patent: WO2007/84786, 2007, A1. Location in patent: Page/Page column 91-92
[2] ACS Medicinal Chemistry Letters, 2011, vol. 2, # 10, p. 774 - 779
[3] Patent: WO2011/130628, 2011, A1. Location in patent: Page/Page column 180
[4] Patent: US2013/102595, 2013, A1. Location in patent: Paragraph 0377; 0378
[5] Patent: JP2015/187145, 2015, A. Location in patent: Paragraph 0330

2-Amino-4-methyl-5-bromopyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Amino-4-methyl-5-bromopyrimidine Suppliers

China 126 India 2 United Kingdom 3 United States 14 Global 145
Pure Chemistry Scientific Inc.
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001-857-928-2050 or 1-888-588-9418
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View Lastest Price from 2-Amino-4-methyl-5-bromopyrimidine manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
2-Amino-4-methyl-5-bromopyrimidine 17321-93-6
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-11-12
Jiangsu Liyang Kunlun Biological Technology Co., Ltd.
Product
5-Bromo-4-methyl-pyrimidin-2-ylamine 17321-93-6
Price
US $0.00-0.00/kg
Min. Order
50kg
Purity
0.99
Supply Ability
20 tons
Release date
2025-03-11
Shanghai Rlavie Technology Co ltd
Product
2-Amino-5-bromo-4-methylpyrimidine 17321-93-6
Price
US $0.00-0.00/kg
Min. Order
0.0001kg
Purity
98%min
Supply Ability
100kgs/month
Release date
2022-05-10

17321-93-6, 2-Amino-4-methyl-5-bromopyrimidineRelated Search:

5-Bromopyrimidine 2-Pyrimidinamine, 4-bromo- (9CI) 2-Aminopyrimidine N,N-Dimethyl-1,4-phenylenediamine Pirimiphos-methyl 2-Amino-5-bromopyrimidine 5-Amino-2-methylpyridine METSULFURON METHYL Kresoxim-methyl Methyl acetate Amino tris(methylene phosphonic acid) Methyl salicylate Methylparaben Bensulfuron methyl Thiophanate-methyl Tris(hydroxymethyl)aminomethane Methyl Methyl bromide

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  • 2-Amino-5-bromo-4-methylpyrimidine
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  • 2-<WBR>AMino-<WBR>5-<WBR>broMo-<WBR>4-<WBR>MethylpyriMidine
  • 2-AMino-5-broMo-4-MethylpyriMidine 97%
  • 100704
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  • 2-Amino-4-methyl-5-bromopyrimidine ISO 9001：2015 REACH
  • 5-Bromo-4-methyl-2-pyrimidinamine
  • 5-Bromo-2-amino-4-methylpyrimidine
  • 17321-93-6
  • Heterocycle-Pyrimidine series