4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride

Product Name: 4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride
CAS No.: 106261-64-7
Chemical Name: 4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride
Synonyms: Imatinib Impurity 48;Imatinib Intermediate 5;4-(4-Methylpiperizinomethyl)benzoylchloride2HCl;4-[(4-Methyl-1-piperazinyl)Methyl]benzoyl chloride;4-(4-Methylpiperazinylmethyl)benzoyl chloride DiHCl;4-(4-Methyl-1-Piperazinyl) Methyl Benzoyl Chloride 2HCl;4-(4-Methyl-1-Piperazinyl) Methyl Benzoyl Chloride 2HCI;4-(4-Methylpiperizinomethyl)benzoylchloridedihydrochloride;4-(4-methylpiperazin-1-yl）benzoyl chloride dihydrochloride;4-(4-METHYLPIPERAZINYLMETHYL)BENZOYL CHLORIDE DIHYDROCHLORIDE
CBNumber: CB01073537
Molecular Formula: C13H18Cl2N2O
Formula Weight: 289.2
MOL File: 106261-64-7.mol

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4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride Property

Melting point:: >240°C (dec.)
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: DMSO (Slightly)
form: Solid
color: White to Off-White
Water Solubility: 100vol% at 20℃[vol%]
Stability:: Hygroscopic, Moisture Sensitive

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Matrix Scientific

Product number: 130570
Product name: 4-(4-Methylpiperazinylmethyl)benzoyl-chloridedihydrochloride
Packaging: 1g
Price: $489
Updated: 2021/12/16

AK Scientific

Product number: 7781BB
Product name: 4-(4-Methylpiperazinylmethyl)benzoylchloridedihydrochloride
Packaging: 1g
Price: $710
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0077286
Product name: 4-(4-METHYLPIPERAZINYLMETHYL)BENZOYL CHLORIDE DIHYDROCHLORIDE
Purity: 95.00%
Packaging: 5G
Price: $909.56
Updated: 2021/12/16

Atlantic Research Chemicals

Product number: CC001336
Product name: 4-(4-Methylpiperazinylmethyl)benzoylchloridedihydrochloride
Purity: 95%
Packaging: 250mgs:
Price: $134.31
Updated: 2021/12/16

Ambeed

Product number: A655772
Product name: 4-((4-Methylpiperazin-1-yl)methyl)benzoylchloridedihydrochloride
Purity: 97+%
Packaging: 1g
Price: $207
Updated: 2021/12/16

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4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride Chemical Properties,Usage,Production

Uses

4-((4-Methylpiperazin-1-yl)methyl)benzoyl Chloride Dihydrochloride is an intermediate in the synthesis of Gleevec N-4-((4-Methylpiperazin-1-yl)methyl)benzaldehyde (G407010), an impurity of Gleevec (G407000), a tyrosine kinase inhibitor which is highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL).

Synthesis

Imaric acid 1g (5g, 0.021 mol, Anegi chemical) into 100mL three-necked bottle, add dichlorosulfoxide (35mL) and catalyst N, N-dimethylformamide (0.3mL), heating reflux reaction for 22 hours, reduced to room temperature, pumping and filtration, n-hexane washing (10mL ?? 2), 45 ~ 50 ?? C drying in vacuum for 2 hours, to obtain a white solid state of 4-(4- 4-(4-methylpiperazinylmethyl)benzoyl chloride dihydrochloride (1h) 5.1g, yield 95%.

4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride Suppliers

China 85 Germany 1 India 9 United States 2 Global 97

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9309
Advantage: 66

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

Shanghai Licheng Chemicals Co., Ltd.

Tel: +86 (21) 5756-1621
Fax: +86 (21) 5756-0637
Email: export@shlcchem.com
Country: China
ProdList: 66
Advantage: 60

Changzhou DongChen Pharmaceutical Co., Ltd.

Tel: 0519-88995800 13815038136
Fax: 0519-88995808
Email: gjf@dcpharmtech.com
Country: China
ProdList: 62
Advantage: 55

Hubei XinyuanShun Chemical Co., Ltd.

Tel: 13971561712, 13995564702, 027-50664929
Fax: 027-50664927
Email: hbeixys2001@163.com
Country: China
ProdList: 3120
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Bide Pharmatech Ltd.

Tel: 400-400-164-7117 18317119277
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 40000
Advantage: 60

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10263
Advantage: 55

Nanjing Chalf-Pharm Technology Co., Ltd.

Tel: 025-57018978 18251899859
Fax: 025-57018008
Email: sales@chalf-pharm.com
Country: China
ProdList: 5666
Advantage: 50

Shanghai QianYan Bio-technology Co., Ltd

Tel: 02781293128
Email: orders@biochemsafebuy.com
Country: China
ProdList: 9923
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

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View Lastest Price from 4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride 106261-64-7
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2024-11-13

Career Henan Chemical Co

Product: 4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride 106261-64-7
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: 100kg
Release date: 2018-12-19

Shanghai Yingrui Biopharma Co., Ltd.

Product: 4-(4-Methylpiperazinylmethyl)benzoylchloridedihydrochloride 106261-64-7
Price: US $0.00/KG
Min. Order: 0KG
Purity: 99%
Supply Ability: 100t
Release date: 2018-03-08

106261-64-7, 4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochlorideRelated Search:

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4-(4-Methylpiperizinomethyl)benzoylchloride2HCl

4-(4-Methylpiperizinomethyl)benzoylchloridedihydrochloride

4-(4-METHYLPIPERAZINYLMETHYL)BENZOYL CHLORIDE DIHYDROCHLORIDE

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4-[(4-Methyl-1-piperazinyl)Methyl]benzoyl chloride

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4-(4-Methylpiperazinylmethyl)benzoyl chloride DiHCl

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4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochlorid...

4-(4-Methyl piperazine-1-yl)methyl benzoyl chloride dihydrochloride

Imatinib Impurity 48

Imatinib Intermediate 5

4-(4-Methyl-1-Piperazinyl) Methyl Benzoyl Chloride 2HCl

4-(4-Methyl-1-Piperazinyl) Methyl Benzoyl Chloride 2HCI

4- (4-methylpiperazine methyl) benzoyl chloride dihydrochloride (Imoyl chloride)

1-[4-(Chlorocarbonyl)benzyl]-4- methylpiperazinediium dichloride

4-(4-Methylpiperazinomethyl)benzoylchloridedihydrochloride(Imatinibacylchloride)

4-(4-Methylpiperazinylmethyl)benzoylchloridedihydrochloride(Imatinibacylchloride)

106261-64-7

C13H19Cl3N2O