ChemicalBook > CAS DataBase List > Exendin-3 (9-39) amide

Exendin-3 (9-39) amide

Product Name
Exendin-3 (9-39) amide
CAS No.
133514-43-9
Chemical Name
Exendin-3 (9-39) amide
Synonyms
EXENDIN (9-39);EXENDIN 3 (9-39);Exendin-4 (9-39);Hexanal Impurity 5;EXENDIN (9-39) AMIDE;EXENDIN FRAGMENT 9-39;EXENDIN-3 (9-39) AMIDE;EXENDIN [9-39] PEPTIDE;Exendin (9-39) Acetate;Exendin 4 (9-39) amide
CBNumber
CB0109941
Molecular Formula
C149H234N40O47S
Formula Weight
3369.76
MOL File
133514-43-9.mol
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Exendin-3 (9-39) amide Property

Density 
1.51
RTECS 
LF2460000
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
H2O : 50 mg/mL (14.84 mM; Need ultrasonic)
form 
Solid
color 
Off-white to pale purple
Water Solubility 
Soluble in water at 1mg/ml
InChIKey
WSEVKKHALHSUMB-UHFFFAOYSA-N
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E7269
Product name
Exendin Fragment 9-39
Purity
≥95% (HPLC)
Packaging
0.1mg
Price
$404
Updated
2024/03/01
Alfa Aesar
Product number
J66126
Product name
Exendin (9-39)
Packaging
0.5mg
Price
$285
Updated
2023/06/20
Alfa Aesar
Product number
J66126
Product name
Exendin (9-39)
Packaging
1mg
Price
$466
Updated
2023/06/20
Cayman Chemical
Product number
19890
Product name
Exendin-3 (9-39) amide
Purity
≥95%
Packaging
500μg
Price
$152
Updated
2024/03/01
Cayman Chemical
Product number
19890
Product name
Exendin-3 (9-39) amide
Purity
≥95%
Packaging
1mg
Price
$214
Updated
2024/03/01
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Exendin-3 (9-39) amide Chemical Properties,Usage,Production

Description

Exendin-3 (9-39) amide is a truncated form of the exendin-4 peptide that acts as a potent competitive antagonist for the glucagon-like peptide 1 receptor (GLP-1R; Kd = 1.7 nM in CHL cells transfected with cloned human GLP-1). It inhibits exendin-3-induced increases in cAMP levels in guinea pig pancreas cells (IC50 = 20 nM). Exendin-3 (9-39) amide administration in the hypothalamus (10 and 100 μg, i.c.v.) reverses GLP-1 inhibition of feeding behavior in rats.

Uses

Biological probe.

Uses

Exendin-3 (9-39) is a potent and selective GLP-1 receptor antagonist.

General Description

Exendin Fragment 9-39 is an antagonist of glucagon-like peptide-1 (GLP-1) receptor, and also acts as an inhibitor of glucosedependent insulinotropic polypeptide (GIP)-receptor binding. It also prevents the production of cAMP by GIP. GLP-1, along with GIP, acts as a physiological incretin.

Biochem/physiol Actions

GLP-1 (glucagon-like peptide-1) receptor antagonist. Competitive inhibitor of exendin-3 and exendin-4.

storage

Store at -20°C

Exendin-3 (9-39) amide Preparation Products And Raw materials

Raw materials

Preparation Products

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Exendin-3 (9-39) amide Suppliers

China 127 Europe 1 France 1 Germany 5 Japan 1 Switzerland 1 United Kingdom 1 United States 19 USA 1 Global 157
MedChemexpress LLC
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View Lastest Price from Exendin-3 (9-39) amide manufacturers

Hebei Mujin Biotechnology Co.,Ltd
Product
Exendin-3 (9-39) amide 133514-43-9
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2024-10-22
Hebei Weibang Biotechnology Co., Ltd
Product
Exendin-3 (9-39) amide 133514-43-9
Price
US $9.90/KG
Min. Order
100KG
Purity
99%
Supply Ability
10 tons
Release date
2024-12-03
Hebei Fengjia New Material Co., Ltd
Product
Exendin-3 (9-39) amide 133514-43-9
Price
US $6.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10000
Release date
2024-08-08

133514-43-9, Exendin-3 (9-39) amideRelated Search:

OMEGA-CONOTOXIN MVIIC SDV-Exendin-3/4 EXENDIN-4 (3-39) Rosiptor Alendronate sodium Topiramate EXENDIN-3 EXENDIN 4, FAM-LABELED Exenatide acetate Exendin-3 (9-39) amide

  • ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2
  • H-ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2
  • EXENDIN 3 (9-39)
  • EXENDIN-3 (9-39) AMIDE
  • EXENDIN (9-39)
  • EXENDIN (9-39) AMIDE
  • EXENDIN [9-39] PEPTIDE
  • EXENDIN FRAGMENT 9-39
  • DLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2
  • M.W. 3369.79 C149H234N40O47S
  • ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2: DLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2
  • Exendin 3 (heloderma horridum), 1-de-L-histidine-2-de-L-serine-3-de-L-aspartic acid-4-deglycine-5-de-L-threonine-6-de-L-phenylalanine-7-de-L-threonine-8-de-L-serine-
  • 9-39-Exendin 3(Heloderma horridum)
  • EXENDIN FRAGMENT 9-39;EXENDIN (9-39)
  • H-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
  • Exendin FragMent 9-39Exendin
  • H-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 acetate salt
  • 9-39-Exendin 3(Heloderma horridum) (9CI)
  • Exendin (9-39) Acetate
  • Exendin 4 (9-39) amide
  • Asp-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRp-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2, ≥95%(HPLC)
  • L-Serinamide, L-α-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparaginylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L-p...
  • Exendin Fragment 9-39 >=95% (HPLC)
  • Exendin-3 (9-39) amide USP/EP/BP
  • GCGR,Glucagon Receptor,Avexitide,Inhibitor,inhibit
  • Exendin-3 (9-39) amide/Avexitide
  • Asp-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TR|p|-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2
  • Exendin-4 (9-39)
  • H-DL-Asp-DL-Leu-DL-Ser-DL-Lys-DL-Gln-DL-Met-DL-Glu-DL-Glu-DL-Glu-DL-Ala-DL-Val-DL-Arg-DL-Leu-DL-Phe-DL-xiIle-DL-Glu-DL-Trp-DL-Leu-DL-Lys-DL-Asn-Gly-Gly-DL-Pro-DL-Ser-DL-Ser-Gly-DL-Ala-DL-Pro-DL-Pro-DL-Pro-DL-Ser-NH2
  • Hexanal Impurity 5
  • Exendin (9-39) amide, GLP-1 receptor antagonist
  • 133514-43-9
  • C149H234N40O47S
  • C149H234N40O47S1
  • Hormones
  • Obesity Research
  • Exendin
  • Cytokines, Growth Factors and Hormones
  • BioChemical
  • Cell Biology
  • Cell Signaling and Neuroscience
  • Peptide
  • GLP-1 Receptor LigandsObesity Research
  • Cytokines Growth Factors and Hormones (Obesity)
  • ExendinPeptides for Cell Biology
  • Hormones
  • Obesity Peptides
  • Obesity Research
  • Other Obesity Research Products
  • Glucagon receptor and related