2-Bromomethylphenylboronic acid
- Product Name
- 2-Bromomethylphenylboronic acid
- CAS No.
- 91983-14-1
- Chemical Name
- 2-Bromomethylphenylboronic acid
- Synonyms
- RARECHEM AH PB 0060;2-BroMoMethylphenylb;o-Boronobenzyl bromide;2-Boronobenzyl bromide;2-Bromomethylphenylboronic;α-Bromo-o-tolueneboronic acid;2-BROMOMETHYLPHENYLBORONIC ACID;2-(Bromomethyl)phenylboronicaci;-(BroMoMethyl)phenylboronic acid;o-(Bromomethyl)phenylboronic Acid
- CBNumber
- CB0131515
- Molecular Formula
- C7H8BBrO2
- Formula Weight
- 214.85
- MOL File
- 91983-14-1.mol
2-Bromomethylphenylboronic acid Property
- Melting point:
- 158-162 °C
- Boiling point:
- 358.5±44.0 °C(Predicted)
- Density
- 1.57±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 8.44±0.58(Predicted)
- form
- crystalline powder
- color
- Faint orange
- InChI
- InChI=1S/C7H8BBrO2/c9-5-6-3-1-2-4-7(6)8(10)11/h1-4,10-11H,5H2
- InChIKey
- MYVJCOQGXCONPE-UHFFFAOYSA-N
- SMILES
- B(C1=CC=CC=C1CBr)(O)O
- CAS DataBase Reference
- 91983-14-1(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 26-36/37/39-36/37-36
- RIDADR
- 3261
- WGK Germany
- 3
- HazardClass
- IRRITANT
- PackingGroup
- III
- HS Code
- 2931900090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 679453
- Product name
- 2-(Bromomethyl)phenylboronic acid
- Packaging
- 1g
- Price
- $26.54
- Updated
- 2025/07/31
- Product number
- 679453
- Product name
- 2-(Bromomethyl)phenylboronic acid
- Packaging
- 5g
- Price
- $158
- Updated
- 2025/07/31
- Product number
- B3600
- Product name
- 2-(Bromomethyl)phenylboronic Acid (contains varying amounts of Anhydride)
- Packaging
- 1g
- Price
- $194
- Updated
- 2025/07/31
- Product number
- B694808
- Product name
- 2-(Bromomethyl)phenylboronic acid
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- B694808
- Product name
- 2-(Bromomethyl)phenylboronic acid
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
2-Bromomethylphenylboronic acid Chemical Properties,Usage,Production
Uses
suzuki reaction
Uses
Reactant involved in:
- Studies of carbon-boron bond cleavage of phenylboronate-pendant cyclen
- Development of a sensory system to detect glucose or other monosaccharides and hydroxycarboxylates
- Synthesis of boronated triaryl and tetraaryl phosphonium salts used in cytotoxicity studies
- Colorimetry and fluorometry mercury determination with chemosensors composed of rhodamine and boronic acid groups
- Synthesis of imidazolium-containing boronic acids used as fluoride ion sensors
- Reactions with adenine for molecules with antiinflammatory antitumor activities?
Synthesis Reference(s)
Journal of the American Chemical Society, 80, p. 835, 1958 DOI: 10.1021/ja01537a021
General Description
May contain varying amounts of anhydride.
Synthesis
16419-60-6
91983-14-1
General procedure for the synthesis of 2-(bromomethyl)benzeneboronic acid from 2-methylbenzeneboronic acid: 14.8 g (0.11 mol) of 2-methylbenzeneboronic acid was added to a 500 mL round bottom flask, followed by the addition of 380 mL of carbon tetrachloride, which was heated slightly until dissolved. A bromine solution was prepared by dissolving 17.9 g of bromine in 85 mL of carbon tetrachloride under light conditions. At the beginning of the reaction, a portion of the bromine solution was added quickly to keep the reaction solution light yellow. After the reaction was carried out for 2 hours, the reaction mixture was bleached with alkaline solution and subsequently filtered. The filter cake was washed five times with carbon tetrachloride and three times with hexane. Finally, the product was dried under vacuum to give 19.97 g of white powdery solid in 84.6% yield.
References
[1] Patent: CN103497211, 2016, B. Location in patent: Paragraph 0242; 0243
[2] Tetrahedron Letters, 2001, vol. 42, # 34, p. 5875 - 5877
[3] Russian Chemical Bulletin, 2005, vol. 54, # 11, p. 2602 - 2611
[4] Russian Chemical Bulletin, 2004, vol. 53, # 2, p. 370 - 375
[5] Chinese Journal of Chemistry, 2011, vol. 29, # 11, p. 2445 - 2450
2-Bromomethylphenylboronic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2-Bromomethylphenylboronic acid Suppliers
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View Lastest Price from 2-Bromomethylphenylboronic acid manufacturers
- Product
- 2-Bromomethylphenylboronic acid 91983-14-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-10
- Product
- 2-(Bromomethyl)phenylboronic Acid (contains varying amounts of Anhydride) 91983-14-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
- Product
- 2-Bromomethylphenylboronic acid 91983-14-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-30