NSC 38280

Product Name: NSC 38280
CAS No.: 70-09-7
Chemical Name: NSC 38280
Synonyms: Wander;Hr 2198;Nsc 60339;NSC 38280;2-Chloro-4',4''-di-2-imidazolin-2-yl-terephthalanilide;inhibit,NSC 60339,NSC60339,NSC-60339,Bacterial,Inhibitor;2-Chloro-N,N'-bis[4-(2-imidazolin-2-yl)phenyl]terephthalamide;Terephthalanilide, 2-chloro-4',4''-di-2-imidazolin-2-yl- (8ci);2-Chloro-N1,N4-bis(4-(4,5-dihydro-1H-imidazol-2-yl)phenyl)terephthalamide;1,4-Benzenedicarboxamide, 2-chloro-N,N'-bis(4-(4,5-dihydro-1H-imidazol-2-yl)phenyl)- (9ci)
CBNumber: CB01323544
Formula Weight: 0
MOL File: 70-09-7.mol

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NSC 38280 Property

storage temp.: Store at -20°C
solubility: DMSO: 5 mg/mL (10.27 mM)
form: Solid
color: Off-white to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0069366
Product name: NSC-60339
Purity: 95.13%
Packaging: 5mg
Price: $450
Updated: 2021/12/16

ChemScene

Product number: CS-0069366
Product name: NSC-60339
Purity: 95.13%
Packaging: 10mg
Price: $780
Updated: 2021/12/16

ChemScene

Product number: CS-0069366
Product name: NSC-60339
Purity: 95.13%
Packaging: 50mg
Price: $2200
Updated: 2021/12/16

ChemScene

Product number: CS-0069366
Product name: NSC-60339
Purity: 95.13%
Packaging: 100mg
Price: $3500
Updated: 2021/12/16

Ambeed

Product number: A1329235
Product name: 2-Chloro-N1,N4-bis(4-(4,5-dihydro-1H-imidazol-2-yl)phenyl)terephthalamide
Purity: 98%
Packaging: 1mg
Price: $247
Updated: 2021/12/16

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NSC 38280 Chemical Properties,Usage,Production

Uses

NSC-60339, an efflux pump inhibitor and a substrate of AcrAB-TolC, is a polybasic terephthalic acid derivative studied as a potential cancer chemotherapeutic agent[1][2].

References

[1] D. W. Yesair, et al. Relationship of Phthalanilide-Lipid Complexes to Uptake and Retention of 2-Chloro-4′,4″-di(2-imidazolin-2-yl)terephthalanilide (NSC 60339) by Sensitive and Resistant P388 Leukemia Cells. CANCER RESEARCH 26 Part 1: 202-207, February 19
[2] Yesair DW, et al. The retention or efflux of phthalanilide (NSC 60339)-lipid complexes by sensitive or resistant murine tumor cells and Escherichia coli B. Cancer Res. 1968 Feb;28(2):314-9. PMID:4868016
[3] Haynes KM, et al. Identification and Structure-Activity Relationships of Novel Compounds that Potentiate the Activities of Antibiotics in Escherichia coli. J Med Chem. 2017 Jul 27;60(14):6205-6219. DOI:10.1021/acs.jmedchem.7b00453
[4] Abdali N, et al. Reviving Antibiotics: Efflux Pump Inhibitors That Interact with AcrA, a Membrane Fusion Protein of the AcrAB-TolC Multidrug Efflux Pump. ACS Infect Dis. 2017 Jan 13;3(1):89-98. DOI:10.1021/acsinfecdis.6b00167

NSC 38280 Preparation Products And Raw materials

Raw materials

Preparation Products

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NSC 38280 Suppliers

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70-09-7, NSC 38280Related Search:

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NSC 38280

2-Chloro-N,N'-bis[4-(2-imidazolin-2-yl)phenyl]terephthalamide

1,4-Benzenedicarboxamide, 2-chloro-N,N'-bis(4-(4,5-dihydro-1H-imidazol-2-yl)phenyl)- (9ci)

2-Chloro-4',4''-di-2-imidazolin-2-yl-terephthalanilide

Hr 2198

Nsc 60339

Terephthalanilide, 2-chloro-4',4''-di-2-imidazolin-2-yl- (8ci)

Wander

2-Chloro-N1,N4-bis(4-(4,5-dihydro-1H-imidazol-2-yl)phenyl)terephthalamide

inhibit,NSC 60339,NSC60339,NSC-60339,Bacterial,Inhibitor

70-09-7