isoliquiritin apioside
- Product Name
- isoliquiritin apioside
- CAS No.
- 120926-46-7
- Chemical Name
- isoliquiritin apioside
- Synonyms
- Neolicuroside;Soliquiritin apioside;isoliquiritin apioside;isoliquiritin apioside USP/EP/BP;Isoliquiritin apioside, 10 mM in DMSO;2-Propen-1-one, 3-[4-[(2-O-D-apio-β-D-furanosyl-β-D-glucopyranosyl)oxy]phenyl]-1-(2,4-dihydroxyphenyl)-, (2E)-;2-Propen-1-one, 3-[4-[(2-O-D-apio-β-D-furanosyl-β-D-glucopyranosyl)oxy]phenyl]-1-(2,4-dihydroxyphenyl)-, (2E)-;(2E)-3-[4-[(2-O-D-apio-beta-D-furanosyl-beta-D-glucopyranosyl)oxy]phenyl]-1-(2,4-dihydroxyphenyl)-2-propen-1-one;(E)-3-[4-[(2S,3R,4S,5S,6R)-3-[(2S,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-1-(2,4-dihydroxyphenyl)prop-2-en-1-one;(E)-3-(4-(((2S,3R,4S,5S,6R)-3-(((2S,3R,4R)-3,4-Dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-1-(2,4-dihydroxyphenyl)prop-2-en-1-one
- CBNumber
- CB01352511
- Molecular Formula
- C26H30O13
- Formula Weight
- 550.51
- MOL File
- 120926-46-7.mol
isoliquiritin apioside Property
- Boiling point:
- 901.0±65.0 °C(Predicted)
- Density
- 1.63
- storage temp.
- -20°C, protect from light
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- pka
- 7.46±0.35(Predicted)
- color
- Yellow to orange
- biological source
- plant
- Water Solubility
- water: slightly soluble
- InChIKey
- VMMVZVPAYFZNBM-KVFWHIKKSA-N
- SMILES
- O([C@@H]1OC[C@]([C@H]1O)(O)CO)[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1OC1C=CC(=CC=1)/C=C/C(C1C=CC(=CC=1O)O)=O)CO)O)O
- CAS DataBase Reference
- 120926-46-7
N-Bromosuccinimide Price
- Product number
- SMB01065
- Product name
- Neolicuroside
- Purity
- ≥85% (LC/MS-ELSD)
- Packaging
- 1mg
- Price
- $382
- Updated
- 2025/07/31
- Product number
- 297261
- Product name
- Isoliquiritin apioside
- Packaging
- 5mg
- Price
- $506
- Updated
- 2021/12/16
- Product number
- 300489
- Product name
- Isoliquiritin apioside
- Packaging
- 10mg
- Price
- $546
- Updated
- 2021/12/16
- Product number
- OI33286
- Product name
- Isoliquiritin apioside
- Packaging
- 1mg
- Price
- $69
- Updated
- 2021/12/16
- Product number
- OI33286
- Product name
- Isoliquiritin apioside
- Packaging
- 2mg
- Price
- $108
- Updated
- 2021/12/16
isoliquiritin apioside Chemical Properties,Usage,Production
Chemical Properties
White powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from licorice.
Uses
Isoliquiritin apioside can be used to resist myocardial ischemia and inhibit the proliferation of HIV.
Definition
ChEBI: Neolicuroside is a member of flavonoids and a glycoside.
Biological Activity
Neolicuroside modulates signaling pathways (e.g., MAPK, NF-KB), impacting vital cell processes such as proliferation, differentiation, and apoptosis. Its multitargeted mechanism includes scavenging free radicals, suppressing pro-inflammatory cytokine production, inhibiting matrix metalloproteinase (MMP) activity and hindering cancer cell growth through apoptosis and cell cycle arrest. Furthermore, it also exerts immunomodulatory effects possibly by activating toll-like receptor 4 (TLR4).
IC 50
MMP9; NF-κB; p38 MAPK
isoliquiritin apioside Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from isoliquiritin apioside manufacturers
- Product
- Isoliquiritin apioside 120926-46-7
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-04-02
- Product
- isoliquiritin apioside 120926-46-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 25kg
- Release date
- 2019-07-12