isodiospyrin

Product Name: isodiospyrin
CAS No.: 20175-84-2
Chemical Name: isodiospyrin
Synonyms: Isoquinone;isodiospyrin;Isodiospirin;[1,2'-BINAPHTHALENE]-5,5',8,8';1,2’-Binaphthalene-5,5’,8,8’-tet;[1,2’-Binaphtalene]-5,5’,8,8’-tet;(-)-1',4-Dihydroxy-2,3'-dimethyl-(1,2'-binaphthalene)-5,5',8,8'-tetrone;[1,2'-Binaphthalene]-5,5',8,8'-tetrone,1',4-dihydroxy-2,3'-dimethyl-, (1R)-;5-hydroxy-6-(4-hydroxy-2-methyl-5,8-dioxonaphthalen-1-yl)-7-methylnaphthalene-1,4-dione;IsodiospyrinQ: What is Isodiospyrin Q: What is the CAS Number of Isodiospyrin Q: What is the storage condition of Isodiospyrin
CBNumber: CB01361355
Molecular Formula: C22H14O6
Formula Weight: 374.34
MOL File: 20175-84-2.mol

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isodiospyrin Property

Melting point:: 233 °C
Boiling point:: 712.0±60.0 °C(Predicted)
Density: 1.495±0.06 g/cm3(Predicted)
pka: 5.66±0.20(Predicted)
form: Solid
color: Orange to red

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

CSNpharm

Product number: CSN15179
Product name: Isodiospyrin
Packaging: 1mg
Price: $425
Updated: 2021/12/16

Arctom

Product number: CFN98019
Product name: Isodiospyrin
Packaging: 5mg
Price: $593
Updated: 2021/12/16

Crysdot

Product number: CD32002067
Product name: Isodiospyrin
Purity: 95+%
Packaging: 5mg
Price: $930
Updated: 2021/12/16

CSNpharm

Product number: CSN15179
Product name: Isodiospyrin
Packaging: 5mg
Price: $1062
Updated: 2021/12/16

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isodiospyrin Chemical Properties,Usage,Production

Uses

Isodiospyrin, a natural dimeric naphthoquinone, is a human DNA topoisomerase I (Topoisomerase) inhibitor. Isodiospyrin can prevent both DNA relaxation and kinase activities of human topoisomerase I. Isodiospyrin shows anticancer, antibacterial and antifungal activities[1][2][3].

Definition

ChEBI: Isodiospyrin is a member of biphenyls.

IC 50

Topoisomerase I

References

[1] Chun-Yuan Ting, et al. Isodiospyrin as a novel human DNA topoisomerase I inhibitor. Biochem Pharmacol. 2003 Nov 15;66(10):1981-91. DOI:10.1016/j.bcp.2003.07.003
[2] B A Adeniyi, et al. Antibacterial activity of diospyrin, isodiospyrin and bisisodiospyrin from the root of Diospyros piscatoria (Gurke) (Ebenaceae). Phytother Res. 2000 Mar;14(2):112-7. DOI:10.1002/(sici)1099-1573(200003)14:2<112::aid-ptr488>3.0.co;2-t
[3] Xiaoning Wang, et al. Antifungal metabolites from the roots of Diospyros virginiana by overpressure layer chromatography. Chem Biodivers. 2011 Dec;8(12):2331-40. DOI:10.1002/cbdv.201000310

isodiospyrin Preparation Products And Raw materials

Raw materials

Preparation Products

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isodiospyrin Suppliers

China 49 India 1 United States 6 Global 56

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isodiospyrin

[1,2’-Binaphtalene]-5,5’,8,8’-tet

1,2’-Binaphthalene-5,5’,8,8’-tet

[1,2'-BINAPHTHALENE]-5,5',8,8'

Isoquinone

(-)-1',4-Dihydroxy-2,3'-dimethyl-(1,2'-binaphthalene)-5,5',8,8'-tetrone

Isodiospirin

[1,2'-Binaphthalene]-5,5',8,8'-tetrone,1',4-dihydroxy-2,3'-dimethyl-, (1R)-

5-hydroxy-6-(4-hydroxy-2-methyl-5,8-dioxonaphthalen-1-yl)-7-methylnaphthalene-1,4-dione

IsodiospyrinQ: What is Isodiospyrin Q: What is the CAS Number of Isodiospyrin Q: What is the storage condition of Isodiospyrin

20175-84-2